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Activation and regulation of the inflammasomes

Overview of attention for article published in Nature Reviews Immunology, May 2013
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (95th percentile)
  • High Attention Score compared to outputs of the same age and source (92nd percentile)

Mentioned by

news
1 news outlet
blogs
2 blogs
twitter
14 X users
patent
16 patents
facebook
1 Facebook page

Citations

dimensions_citation
2395 Dimensions

Readers on

mendeley
2017 Mendeley
citeulike
2 CiteULike
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Title
Activation and regulation of the inflammasomes
Published in
Nature Reviews Immunology, May 2013
DOI 10.1038/nri3452
Pubmed ID
Authors

Eicke Latz, T. Sam Xiao, Andrea Stutz

Abstract

Inflammasomes are key signalling platforms that detect pathogenic microorganisms and sterile stressors, and that activate the highly pro-inflammatory cytokines interleukin-1β (IL-1β) and IL-18. In this Review, we discuss the complex regulatory mechanisms that facilitate a balanced but effective inflammasome-mediated immune response, and we highlight the similarities to another molecular signalling platform - the apoptosome - that monitors cellular health. Extracellular regulatory mechanisms are discussed, as well as the intracellular control of inflammasome assembly, for example, via ion fluxes, free radicals and autophagy.

X Demographics

X Demographics

The data shown below were collected from the profiles of 14 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 2,017 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 9 <1%
Brazil 7 <1%
Germany 6 <1%
United Kingdom 6 <1%
Colombia 5 <1%
Mexico 4 <1%
Spain 3 <1%
Japan 2 <1%
France 2 <1%
Other 17 <1%
Unknown 1956 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 457 23%
Researcher 301 15%
Student > Master 265 13%
Student > Bachelor 240 12%
Student > Doctoral Student 97 5%
Other 311 15%
Unknown 346 17%
Readers by discipline Count As %
Agricultural and Biological Sciences 523 26%
Medicine and Dentistry 291 14%
Biochemistry, Genetics and Molecular Biology 287 14%
Immunology and Microbiology 259 13%
Neuroscience 76 4%
Other 169 8%
Unknown 412 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 36. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 January 2024.
All research outputs
#1,135,852
of 25,837,817 outputs
Outputs from Nature Reviews Immunology
#511
of 2,693 outputs
Outputs of similar age
#8,831
of 210,539 outputs
Outputs of similar age from Nature Reviews Immunology
#3
of 38 outputs
Altmetric has tracked 25,837,817 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,693 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 43.0. This one has done well, scoring higher than 80% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 210,539 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 38 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 92% of its contemporaries.