| Title |
Emerging role of intestinal microbiota and microbial metabolites in metabolic control
|
|---|---|
| Published in |
Diabetologia, December 2016
|
| DOI | 10.1007/s00125-016-4192-0 |
| Pubmed ID | |
| Authors |
Hilde Herrema, Richard G. IJzerman, Max Nieuwdorp |
| Abstract |
The role of the intestinal microbiota and microbial metabolites in the maintenance of host health and development of metabolic disease has gained significant attention over the past decade. Mechanistic insight revealing causality, however, is scarce. Work by Ussar and co-workers demonstrates that a complex interaction between microbiota, host genetics and environmental factors is involved in metabolic disease development in mice. In addition, Perry and co-workers show that the microbial metabolite acetate augments insulin resistance in rats. These studies underscore an important role of the microbiota in the development of obesity and symptoms of type 2 diabetes in rodents. If causality can be demonstrated in humans, development of novel diagnostic and therapeutic tools that target the gut microbiota will have high potential. |
X Demographics
The data shown below were collected from the profiles of 43 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Canada | 4 | 9% |
| United States | 4 | 9% |
| Spain | 3 | 7% |
| Mexico | 3 | 7% |
| United Kingdom | 3 | 7% |
| Germany | 2 | 5% |
| France | 2 | 5% |
| Brazil | 2 | 5% |
| Ireland | 1 | 2% |
| Other | 4 | 9% |
| Unknown | 15 | 35% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 24 | 56% |
| Scientists | 13 | 30% |
| Practitioners (doctors, other healthcare professionals) | 5 | 12% |
| Science communicators (journalists, bloggers, editors) | 1 | 2% |
Mendeley readers
The data shown below were compiled from readership statistics for 117 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | <1% |
| Russia | 1 | <1% |
| Germany | 1 | <1% |
| Unknown | 114 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 24 | 21% |
| Student > Ph. D. Student | 15 | 13% |
| Student > Master | 14 | 12% |
| Student > Bachelor | 13 | 11% |
| Other | 8 | 7% |
| Other | 13 | 11% |
| Unknown | 30 | 26% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 26 | 22% |
| Biochemistry, Genetics and Molecular Biology | 16 | 14% |
| Immunology and Microbiology | 13 | 11% |
| Agricultural and Biological Sciences | 12 | 10% |
| Nursing and Health Professions | 5 | 4% |
| Other | 10 | 9% |
| Unknown | 35 | 30% |
Attention Score in Context
This research output has an Altmetric Attention Score of 34. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 October 2017.
All research outputs
#1,154,013
of 24,885,505 outputs
Outputs from Diabetologia
#633
of 5,311 outputs
Outputs of similar age
#24,154
of 431,188 outputs
Outputs of similar age from Diabetologia
#18
of 65 outputs
Altmetric has tracked 24,885,505 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 5,311 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 24.5. This one has done well, scoring higher than 88% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 431,188 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 94% of its contemporaries.
We're also able to compare this research output to 65 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.