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Mastocytosis: 2016 updated WHO classification and novel emerging treatment concepts

Overview of attention for article published in Blood, December 2016
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (96th percentile)
  • High Attention Score compared to outputs of the same age and source (98th percentile)

Citations

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539 Dimensions

Readers on

mendeley
252 Mendeley
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1 CiteULike
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Title
Mastocytosis: 2016 updated WHO classification and novel emerging treatment concepts
Published in
Blood, December 2016
DOI 10.1182/blood-2016-09-731893
Pubmed ID
Authors

Peter Valent, Cem Akin, Dean D Metcalfe

Abstract

Over the past few years substantial advances have been made in understanding the pathogenesis, evolution, and complexity of mast cell neoplasms. New diagnostic and prognostic parameters and novel therapeutic targets with demonstrable clinical impact have been identified. A number of these new markers, molecular targets, and therapeutic approaches have been validated and translated into clinical practice. At the same time, the classification of mastocytosis and related diagnostic criteria have been refined and updated by the consensus group and the World Health Organization (WHO). As a result, more specific therapies tailored towards prognostic sub-groups of patients have been developed. Emerging treatment concepts employ drugs directed against KIT and other relevant targets in neoplastic mast cells, and will hopefully receive recognition by health authorities in the near future. The current article provides an overview of recent developments in the field, with emphasis on the updated WHO classification, refined criteria, additional prognostic parameters, and novel therapeutic approaches. Based on these emerging concepts, the prognosis, quality of life, and survival of patients with advanced mastocytosis are expected to improve in the coming years.

X Demographics

X Demographics

The data shown below were collected from the profiles of 71 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 252 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 1 <1%
Unknown 251 100%

Demographic breakdown

Readers by professional status Count As %
Other 38 15%
Student > Ph. D. Student 23 9%
Researcher 23 9%
Student > Master 20 8%
Student > Bachelor 19 8%
Other 47 19%
Unknown 82 33%
Readers by discipline Count As %
Medicine and Dentistry 102 40%
Biochemistry, Genetics and Molecular Biology 16 6%
Immunology and Microbiology 8 3%
Agricultural and Biological Sciences 8 3%
Pharmacology, Toxicology and Pharmaceutical Science 5 2%
Other 20 8%
Unknown 93 37%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 59. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 September 2023.
All research outputs
#729,375
of 25,554,853 outputs
Outputs from Blood
#468
of 33,407 outputs
Outputs of similar age
#15,204
of 423,445 outputs
Outputs of similar age from Blood
#16
of 806 outputs
Altmetric has tracked 25,554,853 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 33,407 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.6. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 423,445 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 96% of its contemporaries.
We're also able to compare this research output to 806 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 98% of its contemporaries.