| Title |
Management of HCV infection in the penitentiary setting in the direct-acting antivirals era: practical recommendations from an expert panel
|
|---|---|
| Published in |
Infection, December 2016
|
| DOI | 10.1007/s15010-016-0973-0 |
| Pubmed ID | |
| Authors |
Roberto Ranieri, Giulio Starnini, Sergio Carbonara, Emanuele Pontali, Guido Leo, Antonio Romano, Sandro Panese, Roberto Monarca, Tullio Prestileo, Giorgio Barbarini, Sergio Babudieri |
| Abstract |
The prevalence of HCV infection is higher among prisoners than in the general population. The introduction of HCV direct-acting antivirals (DAA) holds the potential to improve clinical outcomes also in inmates. However, treatment of hepatitis C in inmates has to face several clinical and logistical issues which are peculiar of prison environment. Recommendations on the management of HCV infection specific for the penitentiary setting in the DAA era remain scant. The Italian Society for Penitentiary Medicine and Healthcare has, therefore, issued these recommendations, to provide clinicians with a guide for the comprehensive management of HCV infection in the restriction setting, taking into account its peculiar characteristics. Dedicated diagnostic and treatment procedures should be established in each prison. In particular, the use of DAAs appears crucial to provide patients with an effective therapeutic option, able to overcome the limitations of IFN-based regimens with a short period of treatment. DAA treatment should be initiated as soon as possible in all eligible subjects with the aim to cure the patient, as well as to limit the transmission of HCV infection both inside the penitentiary system and to the free community, once the inmates ends his/her release. Importantly, efforts should be made to open a discussion with regulatory bodies, to define specific regulations aimed to guarantee wide access to effective therapies of all eligible patients, to optimize the management of and the adherence to the HCV treatment, and to ensure the therapeutic continuity after discharge from prison. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 45 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 45 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 10 | 22% |
| Student > Bachelor | 5 | 11% |
| Professor > Associate Professor | 4 | 9% |
| Other | 4 | 9% |
| Student > Doctoral Student | 2 | 4% |
| Other | 8 | 18% |
| Unknown | 12 | 27% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 19 | 42% |
| Nursing and Health Professions | 5 | 11% |
| Environmental Science | 1 | 2% |
| Immunology and Microbiology | 1 | 2% |
| Biochemistry, Genetics and Molecular Biology | 1 | 2% |
| Other | 2 | 4% |
| Unknown | 16 | 36% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 December 2016.
All research outputs
#18,504,575
of 22,925,760 outputs
Outputs from Infection
#1,111
of 1,405 outputs
Outputs of similar age
#309,773
of 420,094 outputs
Outputs of similar age from Infection
#9
of 14 outputs
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So far Altmetric has tracked 1,405 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.5. This one is in the 11th percentile – i.e., 11% of its peers scored the same or lower than it.
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