Title |
Impact of Physical Activity, Cardiorespiratory Fitness, and Exercise Training on Markers of Inflammation
|
---|---|
Published in |
Journal of cardiopulmonary rehabilitation and prevention, May 2011
|
DOI | 10.1097/hcr.0b013e3182122827 |
Pubmed ID | |
Authors |
Carl J. Lavie, Timothy S. Church, Richard V. Milani, Conrad P. Earnest |
Abstract |
Physical activity and exercise training (ET) enhance overall cardiorespiratory fitness (ie, fitness), thus producing many benefits in the primary and secondary prevention of cardiovascular diseases. Substantial evidence also indicates that acute and chronic inflammation is involved in the development and progression of atherosclerosis and major cardiovascular events. The most commonly utilized marker of inflammation is C-reactive protein (CRP). In this review, we discuss the importance of inflammation, especially CRP, as a cardiovascular risk marker by reviewing an abundant cross-sectional and clinical intervention literature providing evidence that physical activity, enhanced fitness, and ET are inversely associated with CRP and that being overweight or obese is directly related with inflammation/CRP. Although we discuss the controversy regarding whether or not ET reduces CRP independent of weight loss, clearly physical activity, improved fitness, and ET are associated with reductions in inflammation and overall cardiovascular risk in both primary and secondary prevention. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 1% |
France | 1 | <1% |
Indonesia | 1 | <1% |
Spain | 1 | <1% |
Brazil | 1 | <1% |
Unknown | 158 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 35 | 21% |
Researcher | 21 | 13% |
Student > Bachelor | 21 | 13% |
Student > Master | 19 | 12% |
Student > Doctoral Student | 11 | 7% |
Other | 31 | 19% |
Unknown | 26 | 16% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 39 | 24% |
Sports and Recreations | 22 | 13% |
Agricultural and Biological Sciences | 18 | 11% |
Nursing and Health Professions | 16 | 10% |
Biochemistry, Genetics and Molecular Biology | 9 | 5% |
Other | 24 | 15% |
Unknown | 36 | 22% |