| Title |
In Vitro Hydrodynamic Assessment of a New Transcatheter Heart Valve Concept (the TRISKELE)
|
|---|---|
| Published in |
Journal of Cardiovascular Translational Research, December 2016
|
| DOI | 10.1007/s12265-016-9722-0 |
| Pubmed ID | |
| Authors |
Benyamin Rahmani, Spyros Tzamtzis, Rose Sheridan, Michael J Mullen, John Yap, Alexander M. Seifalian, Gaetano Burriesci |
| Abstract |
This study presents the in vitro hydrodynamic assessment of the TRISKELE, a new system suitable for transcatheter aortic valve implantation (TAVI), aiming to mitigate the procedural challenges experienced with current technologies. The TRISKELE valve comprises three polymeric leaflet and an adaptive sealing cuff, supported by a novel fully retrievable self-expanding nitinol wire frame. Valve prototypes were manufactured in three sizes of 23, 26, and 29 mm by automated dip-coating of a biostable polymer, and tested in a hydrodynamic bench setup in mock aortic roots of 21, 23, 25, and 27 mm annulus, and compared to two reference valves suitable for equivalent implantation ranges: Edwards SAPIEN XT and Medtronic CoreValve. The TRISKELE valves demonstrated a global hydrodynamic performance comparable or superior to the controls with significant reduction in paravalvular leakage. The TRISKELE valve exhibits enhanced anchoring and improved sealing. The valve is currently under preclinical investigation. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 33% |
| Unknown | 2 | 67% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 67% |
| Practitioners (doctors, other healthcare professionals) | 1 | 33% |
Mendeley readers
The data shown below were compiled from readership statistics for 77 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Belgium | 1 | 1% |
| Unknown | 76 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 15 | 19% |
| Researcher | 15 | 19% |
| Student > Master | 7 | 9% |
| Student > Bachelor | 4 | 5% |
| Student > Doctoral Student | 4 | 5% |
| Other | 7 | 9% |
| Unknown | 25 | 32% |
| Readers by discipline | Count | As % |
|---|---|---|
| Engineering | 25 | 32% |
| Medicine and Dentistry | 11 | 14% |
| Agricultural and Biological Sciences | 3 | 4% |
| Materials Science | 3 | 4% |
| Business, Management and Accounting | 2 | 3% |
| Other | 4 | 5% |
| Unknown | 29 | 38% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 July 2017.
All research outputs
#13,814,547
of 22,925,760 outputs
Outputs from Journal of Cardiovascular Translational Research
#304
of 578 outputs
Outputs of similar age
#218,358
of 420,925 outputs
Outputs of similar age from Journal of Cardiovascular Translational Research
#5
of 8 outputs
Altmetric has tracked 22,925,760 research outputs across all sources so far. This one is in the 39th percentile – i.e., 39% of other outputs scored the same or lower than it.
So far Altmetric has tracked 578 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.5. This one is in the 47th percentile – i.e., 47% of its peers scored the same or lower than it.
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We're also able to compare this research output to 8 others from the same source and published within six weeks on either side of this one. This one has scored higher than 3 of them.