| Title |
HER2-specific T lymphocytes kill both trastuzumab-resistant and trastuzumab-sensitive breast cell lines in vitro
|
|---|---|
| Published in |
Chinese Journal of Cancer Research, May 2012
|
| DOI | 10.1007/s11670-012-0143-6 |
| Pubmed ID | |
| Authors |
Xiao-lin Lin, Xiao-li Wang, Bo Ma, Jun Jia, Ying Yan, Li-jun Di, Yan-hua Yuan, Feng-ling Wan, Yuan-li Lu, Xu Liang, Tao Shen, Jun Ren |
| Abstract |
Although the development of trastuzumab has improved the outlook for women with human epidermal growth factor receptor 2 (HER2)-positive breast cancer, the resistance to anti-HER2 therapy is a growing clinical dilemma. We aim to determine whether HER2-specific T cells generated from dendritic cells (DCs) modified with HER2 gene could effectively kill the HER2-positive breast cancer cells, especially the trastuzumab-resistant cells. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 19 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 5% |
| South Africa | 1 | 5% |
| Unknown | 17 | 89% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 3 | 16% |
| Student > Ph. D. Student | 3 | 16% |
| Student > Bachelor | 2 | 11% |
| Lecturer | 2 | 11% |
| Student > Master | 2 | 11% |
| Other | 2 | 11% |
| Unknown | 5 | 26% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 6 | 32% |
| Medicine and Dentistry | 2 | 11% |
| Nursing and Health Professions | 2 | 11% |
| Unspecified | 1 | 5% |
| Immunology and Microbiology | 1 | 5% |
| Other | 1 | 5% |
| Unknown | 6 | 32% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 June 2013.
All research outputs
#18,340,012
of 22,711,645 outputs
Outputs from Chinese Journal of Cancer Research
#140
of 239 outputs
Outputs of similar age
#126,446
of 164,271 outputs
Outputs of similar age from Chinese Journal of Cancer Research
#3
of 4 outputs
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So far Altmetric has tracked 239 research outputs from this source. They receive a mean Attention Score of 2.7. This one is in the 30th percentile – i.e., 30% of its peers scored the same or lower than it.
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