Title |
Genetic variants in telomerase-related genes are associated with an older age at diagnosis in glioma patients: evidence for distinct pathways of gliomagenesis
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Published in |
Neuro-Oncology, June 2013
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DOI | 10.1093/neuonc/not051 |
Pubmed ID | |
Authors |
Kyle M Walsh, Terri Rice, Paul A Decker, Matthew L Kosel, Thomas Kollmeyer, Helen M Hansen, Shichun Zheng, Lucie S McCoy, Paige M Bracci, Erik Anderson, George Hsuang, Joe L Wiemels, Alexander R Pico, Ivan Smirnov, Annette M Molinaro, Tarik Tihan, Mitchell S Berger, Susan M Chang, Michael D Prados, Daniel H Lachance, Hugues Sicotte, Jeanette E Eckel-Passow, John K Wiencke, Robert B Jenkins, Margaret R Wrensch |
Abstract |
Genome-wide association studies have implicated single nucleotide polymorphisms (SNPs) in 7 genes as glioma risk factors, including 2 (TERT, RTEL1) involved in telomerase structure/function. We examined associations of these 7 established glioma risk loci with age at diagnosis among patients with glioma. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
India | 1 | 17% |
Ireland | 1 | 17% |
United Kingdom | 1 | 17% |
Unknown | 3 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 3 | 50% |
Scientists | 1 | 17% |
Practitioners (doctors, other healthcare professionals) | 1 | 17% |
Science communicators (journalists, bloggers, editors) | 1 | 17% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 1 | 3% |
United States | 1 | 3% |
Unknown | 32 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 9 | 26% |
Researcher | 5 | 15% |
Student > Bachelor | 4 | 12% |
Student > Master | 4 | 12% |
Professor | 2 | 6% |
Other | 4 | 12% |
Unknown | 6 | 18% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 9 | 26% |
Biochemistry, Genetics and Molecular Biology | 7 | 21% |
Medicine and Dentistry | 7 | 21% |
Nursing and Health Professions | 1 | 3% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 3% |
Other | 2 | 6% |
Unknown | 7 | 21% |