| Title |
Commercially available lifestyle modification program: randomized controlled trial addressing heart and bone health in BRCA1/2+ breast cancer survivors after risk-reducing salpingo-oophorectomy
|
|---|---|
| Published in |
Journal of Cancer Survivorship, November 2016
|
| DOI | 10.1007/s11764-016-0582-z |
| Pubmed ID | |
| Authors |
Kathleen M. Sturgeon, Lorraine T. Dean, Mariane Heroux, Jessica Kane, Toni Bauer, Erica Palmer, Jin Long, Shannon Lynch, Linda Jacobs, David B. Sarwer, Mary B. Leonard, Kathryn Schmitz |
| Abstract |
The goal of this RCT was to examine the efficacy and safety of a web-based program to improve cardiovascular and bone health outcomes, among 35 BRCA1/2+ breast cancer survivors who underwent prophylactic oophorectomy and thus experienced premature surgical menopause. A 12-month commercially available web-based lifestyle modification program (Precision Nutrition Coaching) was utilized. Cardiovascular fitness, dietary intake, leisure time activity, body composition, bone mineral density, bone structure, and muscle strength were assessed. Average adherence to all program components was 74.8 %. Women in the intervention group maintained their cardiovascular fitness level over the 12 months (1.1 ± 7.9 %), while the control group significantly decreased fitness capacity (-4.0 ± 7.5 %). There was a significant difference between groups in percent change of whole body bone area (-0.8 ± 2.5 control and 0.5 ± 1.30 intervention). We also observed decreased BMI (-4.7 ± 6.2 %) and fat mass (-8.6 ± 12.7 %) in the intervention group due to significant concomitant decreases in caloric intake and increases in caloric expenditure. The control group demonstrated decreased caloric intake and decreased lean tissue mass. In this population at high risk for detrimental cardiovascular and bone outcomes, a commercially available lifestyle intervention program mitigated a decline in cardiovascular health, improved bone health, and decreased weight through fat loss. Precision Nutrition Coaching has shown benefit in breast cancer survivors for reduced risk of deleterious cardiovascular and bone outcomes. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 276 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 276 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 41 | 15% |
| Student > Master | 32 | 12% |
| Student > Ph. D. Student | 22 | 8% |
| Researcher | 16 | 6% |
| Student > Doctoral Student | 14 | 5% |
| Other | 46 | 17% |
| Unknown | 105 | 38% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 43 | 16% |
| Nursing and Health Professions | 37 | 13% |
| Sports and Recreations | 23 | 8% |
| Unspecified | 12 | 4% |
| Psychology | 9 | 3% |
| Other | 28 | 10% |
| Unknown | 124 | 45% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 February 2017.
All research outputs
#13,132,432
of 23,149,216 outputs
Outputs from Journal of Cancer Survivorship
#607
of 993 outputs
Outputs of similar age
#197,983
of 416,496 outputs
Outputs of similar age from Journal of Cancer Survivorship
#7
of 10 outputs
Altmetric has tracked 23,149,216 research outputs across all sources so far. This one is in the 42nd percentile – i.e., 42% of other outputs scored the same or lower than it.
So far Altmetric has tracked 993 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.4. This one is in the 37th percentile – i.e., 37% of its peers scored the same or lower than it.
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