| Title |
KRAS, NRAS and BRAF mutations in colorectal cancer and melanoma
|
|---|---|
| Published in |
Medical Oncology, January 2017
|
| DOI | 10.1007/s12032-016-0879-9 |
| Pubmed ID | |
| Authors |
Jonas Cicenas, Linas Tamosaitis, Kotryna Kvederaviciute, Ricardas Tarvydas, Gintare Staniute, Karthik Kalyan, Edita Meskinyte-Kausiliene, Vaidotas Stankevicius, Mindaugas Valius |
| Abstract |
Cancers are the group of diseases, which arise because of the uncontrolled behavior of some of the genes in our cells. There are possibilities of gene amplifications, overexpressions, deletions and other anomalies which might lead to the development and spread of cancer. One of the most dangerous ways to the cancers is the mutations of the genes. The mutated genes can start unstoppable proliferation of cells, their uncontrolled motility, protection from apoptosis, the DNA mutation enhancement as well as other anomalies, leading to the cancer. This review focuses on the genes, which are frequently mutated in various cancers and are known to be important in the advance and progression of colorectal cancer and melanoma, namely KRAS, NRAS and BRAF. |
X Demographics
The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 17% |
| Lithuania | 1 | 17% |
| Switzerland | 1 | 17% |
| Unknown | 3 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 67% |
| Science communicators (journalists, bloggers, editors) | 1 | 17% |
| Scientists | 1 | 17% |
Mendeley readers
The data shown below were compiled from readership statistics for 160 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Portugal | 1 | <1% |
| Poland | 1 | <1% |
| Germany | 1 | <1% |
| Brazil | 1 | <1% |
| Unknown | 156 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 29 | 18% |
| Student > Bachelor | 23 | 14% |
| Student > Master | 19 | 12% |
| Researcher | 17 | 11% |
| Other | 13 | 8% |
| Other | 20 | 13% |
| Unknown | 39 | 24% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 50 | 31% |
| Medicine and Dentistry | 24 | 15% |
| Agricultural and Biological Sciences | 15 | 9% |
| Pharmacology, Toxicology and Pharmaceutical Science | 6 | 4% |
| Chemistry | 4 | 3% |
| Other | 17 | 11% |
| Unknown | 44 | 28% |
Attention Score in Context
This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 January 2023.
All research outputs
#3,707,777
of 23,510,717 outputs
Outputs from Medical Oncology
#68
of 1,328 outputs
Outputs of similar age
#72,988
of 424,392 outputs
Outputs of similar age from Medical Oncology
#2
of 16 outputs
Altmetric has tracked 23,510,717 research outputs across all sources so far. Compared to these this one has done well and is in the 84th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,328 research outputs from this source. They receive a mean Attention Score of 3.1. This one has done particularly well, scoring higher than 94% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 424,392 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 82% of its contemporaries.
We're also able to compare this research output to 16 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 87% of its contemporaries.