Title |
Development of a standard treatment protocol for severe acute respiratory syndrome
|
---|---|
Published in |
The Lancet, May 2003
|
DOI | 10.1016/s0140-6736(03)13265-5 |
Pubmed ID | |
Authors |
Loletta K-Y So, Arthur CW Lau, Loretta YC Yam, Thomas MT Cheung, Edwin Poon, Raymond WH Yung, KY Yuen |
Abstract |
A series of 31 patients with probable SARS, diagnosed from WHO criteria, were treated according to a treatment protocol consisting of antibacterials and a combination of ribavirin and methylprednisolone. Through experience with the first 11 patients, we were able to finalise standard dose regimens, including pulsed methylprednisolone. One patient recovered on antibacterial treatment alone, 17 showed rapid and sustained responses, and 13 achieved improvement with step-up or pulsed methylprednisolone. Four patients required short periods of non-invasive ventilation. No patient required intubation or mechanical ventilation. There was no mortality or treatment morbidity in this series. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 37 | 10% |
United States | 34 | 9% |
Australia | 12 | 3% |
Canada | 10 | 3% |
Netherlands | 3 | <1% |
Poland | 3 | <1% |
Germany | 2 | <1% |
France | 2 | <1% |
Trinidad and Tobago | 1 | <1% |
Other | 16 | 4% |
Unknown | 266 | 69% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 363 | 94% |
Scientists | 10 | 3% |
Practitioners (doctors, other healthcare professionals) | 7 | 2% |
Science communicators (journalists, bloggers, editors) | 6 | 2% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Germany | 1 | <1% |
Unknown | 114 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 18 | 16% |
Student > Master | 18 | 16% |
Student > Bachelor | 11 | 10% |
Student > Ph. D. Student | 8 | 7% |
Other | 6 | 5% |
Other | 27 | 23% |
Unknown | 27 | 23% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 27 | 23% |
Agricultural and Biological Sciences | 9 | 8% |
Biochemistry, Genetics and Molecular Biology | 7 | 6% |
Nursing and Health Professions | 5 | 4% |
Immunology and Microbiology | 5 | 4% |
Other | 21 | 18% |
Unknown | 41 | 36% |