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(S)-[6]-Gingerol inhibits TGF-β-stimulated biglycan synthesis but not glycosaminoglycan hyperelongation in human vascular smooth muscle cells

Overview of attention for article published in Journal of Pharmacy & Pharmacology, March 2013
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Citations

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33 Dimensions

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21 Mendeley
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Title
(S)-[6]-Gingerol inhibits TGF-β-stimulated biglycan synthesis but not glycosaminoglycan hyperelongation in human vascular smooth muscle cells
Published in
Journal of Pharmacy & Pharmacology, March 2013
DOI 10.1111/jphp.12060
Pubmed ID
Authors

Danielle Kamato, Hossein Babaahmadi Rezaei, Robel Getachew, Lyna Thach, Daniel Guidone, Narin Osman, Basil Roufogalis, Colin C Duke, Van Hoan Tran, Wenhua Zheng, Peter J Little

Abstract

(S)-[6]-Gingerol is under investigation for a variety of therapeutic uses. Transforming growth factor (TGF)-β stimulates proteoglycan synthesis, leading to increased binding of low-density lipoproteins, which is the initiating step in atherosclerosis. We evaluated the effects of (S)-[6]-gingerol on these TGF-β-mediated proteoglycan changes to explore its potential as an anti-atherosclerotic agent.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 21 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 5%
Unknown 20 95%

Demographic breakdown

Readers by professional status Count As %
Researcher 3 14%
Librarian 2 10%
Student > Doctoral Student 2 10%
Student > Ph. D. Student 2 10%
Student > Postgraduate 2 10%
Other 7 33%
Unknown 3 14%
Readers by discipline Count As %
Pharmacology, Toxicology and Pharmaceutical Science 5 24%
Nursing and Health Professions 2 10%
Agricultural and Biological Sciences 2 10%
Medicine and Dentistry 2 10%
Biochemistry, Genetics and Molecular Biology 1 5%
Other 4 19%
Unknown 5 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 July 2013.
All research outputs
#20,674,485
of 25,394,764 outputs
Outputs from Journal of Pharmacy & Pharmacology
#2,632
of 3,125 outputs
Outputs of similar age
#161,803
of 210,340 outputs
Outputs of similar age from Journal of Pharmacy & Pharmacology
#8
of 12 outputs
Altmetric has tracked 25,394,764 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,125 research outputs from this source. They receive a mean Attention Score of 4.3. This one is in the 8th percentile – i.e., 8% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 210,340 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one is in the 33rd percentile – i.e., 33% of its contemporaries scored the same or lower than it.