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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Soluble transferrin receptor and risk of type 2 diabetes in the obese and nonobese
|
|---|---|
| Published in |
European Journal of Clinical Investigation, February 2017
|
| DOI | 10.1111/eci.12725 |
| Pubmed ID | |
| Authors |
José C. Fernández‐Cao, Victoria Arija, Núria Aranda, Josep Basora, Javier Diez‐Espino, Ramón Estruch, Montse Fitó, Dolores Corella, Jordi Salas‐Salvadó |
| Abstract |
Studies evaluating the relationship between soluble transferrin receptor (sTfR), a biomarker inversely related to body iron stores, and risk of type 2 diabetes mellitus (T2DM) are scarce and inconclusive. Furthermore, sTfR concentrations have been observed to be significantly higher in obese than in non-obese individuals. Therefore, the aim of the present study was to assess the relationship between sTfR and the risk of T2DM in obese and non-obese subjects. A nested case-control study of 153 cases of newly diagnosed diabetic subjects, 73 obese and 80 non-obese, and 306 individually matched-controls, 138 obese and 166 non-obese, who did not develop T2DM for a median 6-year follow-up (interquartile range: 3.9-6.5) was conducted using data from the PREDIMED (PREvention with MEDiterranean Diet) cohort (http://www.controlled-trials.com/ISRCTN35739639). Cases and controls were matched for age (≤67 vs. >67years), gender, dietary intervention group, and BMI (≤27 vs. >27kg/m(2) ). Waist circumference is the main determinant of sTfR concentrations in the whole sample (β=0.476, P<0.001), in the obese (β=0.802, P<0.001) and the non-obese (β=0.455, P=0.003). Furthermore, sTfR is directly associated with the risk of T2DM in obese individuals (OR=2.79; 95% CI:1.35-5.77, P=0.005) and inversely associated in non-obese individuals (OR=0.40; 95% CI:0.20-0.79, P=0.015). The association between sTfR levels and risk of T2DM in a population at high cardiovascular risk depend on the presence or absence of obesity. While in non-obese subjects elevated sTfR levels are associated with a decreased risk of developing T2DM, in obese subjects the risk increases. This suggests that obesity alters the relationship between sTfR and T2DM incidence. This article is protected by copyright. All rights reserved. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 60 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 60 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 14 | 23% |
| Researcher | 8 | 13% |
| Student > Master | 8 | 13% |
| Student > Ph. D. Student | 7 | 12% |
| Student > Doctoral Student | 3 | 5% |
| Other | 9 | 15% |
| Unknown | 11 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 17 | 28% |
| Nursing and Health Professions | 12 | 20% |
| Agricultural and Biological Sciences | 5 | 8% |
| Biochemistry, Genetics and Molecular Biology | 3 | 5% |
| Social Sciences | 3 | 5% |
| Other | 8 | 13% |
| Unknown | 12 | 20% |
Attention Score in Context
This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 April 2017.
All research outputs
#3,261,171
of 24,549,201 outputs
Outputs from European Journal of Clinical Investigation
#222
of 1,898 outputs
Outputs of similar age
#66,897
of 432,918 outputs
Outputs of similar age from European Journal of Clinical Investigation
#1
of 14 outputs
Altmetric has tracked 24,549,201 research outputs across all sources so far. Compared to these this one has done well and is in the 86th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,898 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 30.6. This one has done well, scoring higher than 88% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 432,918 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 84% of its contemporaries.
We're also able to compare this research output to 14 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 92% of its contemporaries.