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Alterations in Expression Pattern of Splicing Factors in Epithelial Ovarian Cancer and its Clinical Impact

Overview of attention for article published in International Journal of Gynecological Cancer, April 2013
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Title
Alterations in Expression Pattern of Splicing Factors in Epithelial Ovarian Cancer and its Clinical Impact
Published in
International Journal of Gynecological Cancer, April 2013
DOI 10.1097/igc.0b013e31829783e3
Pubmed ID
Authors

Severine Iborra, Marc Hirschfeld, Markus Jaeger, Axel zur Hausen, Iona Braicu, Jalid Sehouli, Gerald Gitsch, Elmar Stickeler

Abstract

Alternative splicing represents an important nuclear mechanism in the posttranscriptional regulation of gene expression, which is frequently altered during tumorigenesis. Previously, we described marked changes in alternative splicing of the CD44 gene in ovarian and breast cancer as well as specific induction of distinct splicing factors during tumor development. The present study was focused on the expression profiles of different splicing factors, including classical serine-arginine (SR) proteins including ASF/SF2, hTra2β1, hTra2α, and Y-box-binding protein (YB-1) in physiological and malignant epithelial ovarian tissue to evaluate their expression pattern with regard to tumor development and disease progression.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 32 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 32 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 11 34%
Student > Bachelor 6 19%
Student > Master 2 6%
Student > Postgraduate 2 6%
Researcher 2 6%
Other 1 3%
Unknown 8 25%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 13 41%
Agricultural and Biological Sciences 7 22%
Pharmacology, Toxicology and Pharmaceutical Science 1 3%
Veterinary Science and Veterinary Medicine 1 3%
Medicine and Dentistry 1 3%
Other 1 3%
Unknown 8 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 October 2013.
All research outputs
#20,656,161
of 25,373,627 outputs
Outputs from International Journal of Gynecological Cancer
#2,203
of 3,440 outputs
Outputs of similar age
#160,704
of 209,603 outputs
Outputs of similar age from International Journal of Gynecological Cancer
#19
of 67 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,440 research outputs from this source. They receive a mean Attention Score of 4.7. This one is in the 7th percentile – i.e., 7% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 209,603 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 67 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.