| Title |
Islet encapsulation: advances and obstacles
|
|---|---|
| Published in |
Diabetologia, April 2013
|
| DOI | 10.1007/s00125-013-2921-1 |
| Pubmed ID | |
| Authors |
G. C. Weir |
| Abstract |
It has been known for decades that encapsulation can protect transplanted islets from immune destruction in rodents, but it has proved difficult to extend this success to large animals and humans. A new study in this issue by Jacobs-Tulleneers-Thevissen et al (doi: 10.1007/s00125-013-2906-0 ) advances the field by showing that human islets contained in alginate capsules can function very well, not only in the peritoneal cavity of mice, but also in a human with type 1 diabetes. Many obstacles must still be overcome, but this technology has the potential to safely protect transplanted beta cells from autoimmunity and allorejection. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 85 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 4% |
| Sweden | 1 | 1% |
| Portugal | 1 | 1% |
| Spain | 1 | 1% |
| Mexico | 1 | 1% |
| Unknown | 78 | 92% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 28 | 33% |
| Researcher | 14 | 16% |
| Student > Master | 11 | 13% |
| Student > Bachelor | 10 | 12% |
| Student > Doctoral Student | 4 | 5% |
| Other | 11 | 13% |
| Unknown | 7 | 8% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 17 | 20% |
| Medicine and Dentistry | 16 | 19% |
| Engineering | 13 | 15% |
| Biochemistry, Genetics and Molecular Biology | 11 | 13% |
| Materials Science | 4 | 5% |
| Other | 16 | 19% |
| Unknown | 8 | 9% |
Attention Score in Context
This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 October 2021.
All research outputs
#6,259,133
of 22,711,645 outputs
Outputs from Diabetologia
#2,537
of 5,029 outputs
Outputs of similar age
#52,279
of 192,343 outputs
Outputs of similar age from Diabetologia
#19
of 49 outputs
Altmetric has tracked 22,711,645 research outputs across all sources so far. This one has received more attention than most of these and is in the 72nd percentile.
So far Altmetric has tracked 5,029 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 22.6. This one is in the 49th percentile – i.e., 49% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 192,343 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.
We're also able to compare this research output to 49 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 61% of its contemporaries.