Title |
IL-9 and Th9 in parasite immunity
|
---|---|
Published in |
Seminars in Immunopathology, November 2016
|
DOI | 10.1007/s00281-016-0606-9 |
Pubmed ID | |
Authors |
P. Licona-Limón, A. Arias-Rojas, E. Olguín-Martínez |
Abstract |
Interleukin-9 is a cytokine classically related to type 2 immune responses whose cellular identity has been recently reevaluated to identify a new specialized T helper subset called Th9 and an innate source referred as innate lymphoid cell type 2. Over the past years, IL-9 has been associated with allergic responses, tumor immunology, and autoimmunity; however, in this review, we will specifically focus on the role of IL-9 and Th9 cells in the context of parasitic infections. We will summarize and discuss all the evidence relating IL-9 expression and function in parasitic infections with a particular emphasis in helminth infections, an important health issue in developing countries; we will also provide a general description and classification of parasites, the immune response and cellular compartments activated in this context, and its implications and future directions towards a complete understanding of this interesting new T helper subset and its potential therapeutic use. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 67% |
United Kingdom | 1 | 33% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 67% |
Scientists | 1 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 54 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 10 | 19% |
Researcher | 9 | 17% |
Student > Master | 5 | 9% |
Student > Doctoral Student | 5 | 9% |
Student > Ph. D. Student | 4 | 7% |
Other | 9 | 17% |
Unknown | 12 | 22% |
Readers by discipline | Count | As % |
---|---|---|
Immunology and Microbiology | 13 | 24% |
Biochemistry, Genetics and Molecular Biology | 8 | 15% |
Medicine and Dentistry | 6 | 11% |
Agricultural and Biological Sciences | 6 | 11% |
Veterinary Science and Veterinary Medicine | 4 | 7% |
Other | 3 | 6% |
Unknown | 14 | 26% |