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Tactile interactions lead to coherent motion and enhanced chemotaxis of migrating cells

Overview of attention for article published in Physical Biology, June 2013
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  • Good Attention Score compared to outputs of the same age and source (75th percentile)

Mentioned by

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2 X users
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1 research highlight platform

Citations

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47 Dimensions

Readers on

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92 Mendeley
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2 CiteULike
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Title
Tactile interactions lead to coherent motion and enhanced chemotaxis of migrating cells
Published in
Physical Biology, June 2013
DOI 10.1088/1478-3975/10/4/046002
Pubmed ID
Authors

Luke Coburn, Luca Cerone, Colin Torney, Iain D Couzin, Zoltan Neufeld

Abstract

When motile cells come into contact with one another their motion is often considerably altered. In a process termed contact inhibition of locomotion (CIL) cells reshape and redirect their movement as a result of cell-cell contact. Here we describe a mathematical model that demonstrates that CIL alone is sufficient to produce coherent, collective cell migration. Our model illustrates a possible mechanism behind collective cell migration that is observed, for example, in neural crest cells during development, and in metastasizing cancer cells. We analyse the effects of varying cell density and shape on the alignment patterns produced and the transition to coherent motion. Finally, we demonstrate that this process may have important functional consequences by enhancing the accuracy and robustness of the chemotactic response, and factors such as cell shape and cell density are more significant determinants of migration accuracy than the individual capacity to detect environmental gradients.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 92 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 3 3%
United Kingdom 1 1%
France 1 1%
Unknown 87 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 29 32%
Researcher 20 22%
Student > Master 9 10%
Professor > Associate Professor 7 8%
Student > Postgraduate 3 3%
Other 9 10%
Unknown 15 16%
Readers by discipline Count As %
Agricultural and Biological Sciences 24 26%
Physics and Astronomy 19 21%
Engineering 11 12%
Mathematics 6 7%
Biochemistry, Genetics and Molecular Biology 4 4%
Other 11 12%
Unknown 17 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 November 2013.
All research outputs
#14,599,900
of 25,373,627 outputs
Outputs from Physical Biology
#242
of 656 outputs
Outputs of similar age
#110,492
of 210,217 outputs
Outputs of similar age from Physical Biology
#2
of 8 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 41st percentile – i.e., 41% of other outputs scored the same or lower than it.
So far Altmetric has tracked 656 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.3. This one has gotten more attention than average, scoring higher than 62% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 210,217 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 46th percentile – i.e., 46% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 8 others from the same source and published within six weeks on either side of this one. This one has scored higher than 6 of them.