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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Reproducibility of tract‐based white matter microstructural measures using the ENIGMA‐DTI protocol
|
|---|---|
| Published in |
Brain and Behavior, January 2017
|
| DOI | 10.1002/brb3.615 |
| Pubmed ID | |
| Authors |
Ashley Acheson, S. Andrea Wijtenburg, Laura M. Rowland, Anderson Winkler, Charles W. Mathias, L. Elliot Hong, Neda Jahanshad, Binish Patel, Paul M. Thompson, Stephen A. McGuire, Paul M. Sherman, Peter Kochunov, Donald M. Dougherty |
| Abstract |
In preparation for longitudinal analyses of white matter development in youths with family histories of substance use disorders (FH+) or without such histories (FH-), we examined the reproducibility and reliability of global and regional measures of fractional anisotropy (FA) values, measured using the Enhancing Neuro Imaging Genetics Through Meta Analysis (ENIGMA)-diffusion tensor imaging (DTI) protocol. Highly reliable measures are necessary to detect any subtle differences in brain development. First, we analyzed reproducibility data in a sample of 12 healthy young adults (ages 20-28) imaged three times within a week. Next, we calculated the same metrics in data collected 1-year apart in the sample of 68 FH+ and 21 FH- adolescents. This is a timeframe where within subject changes in white matter microstructure are small compared to between subject variance. Reproducibility was estimated by examining mean coefficients of variation (MCV), mean absolute differences (MAD), and intraclass correlations (ICC) for global and tract-specific FA values. We found excellent reproducibility for whole-brain DTI-FA values and most of the white matter tracts, except for the corticospinal tract and the fornix in both adults and youths. There was no significant effect of FH-group on reproducibility (p = .4). Reproducibility metrics were not significantly different between adolescents and adults (all p > .2). In post hoc analyses, the reproducibility metrics for regional FA values showed a strong positive correlation (r = .6) with the regional FA heritability measures previously reported by ENIGMA-DTI. Overall, this study demonstrated an excellent reproducibility of ENIGMA-DTI FA, positing it as viable analysis tools for longitudinal studies and other protocols that repeatedly assess white matter microstructure. |
X Demographics
The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 20% |
| Unknown | 4 | 80% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 80% |
| Science communicators (journalists, bloggers, editors) | 1 | 20% |
Mendeley readers
The data shown below were compiled from readership statistics for 58 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 2% |
| Unknown | 57 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 12 | 21% |
| Researcher | 10 | 17% |
| Professor > Associate Professor | 5 | 9% |
| Student > Bachelor | 3 | 5% |
| Student > Doctoral Student | 3 | 5% |
| Other | 9 | 16% |
| Unknown | 16 | 28% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 10 | 17% |
| Medicine and Dentistry | 8 | 14% |
| Psychology | 7 | 12% |
| Agricultural and Biological Sciences | 3 | 5% |
| Nursing and Health Professions | 1 | 2% |
| Other | 4 | 7% |
| Unknown | 25 | 43% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 October 2017.
All research outputs
#15,755,393
of 25,394,764 outputs
Outputs from Brain and Behavior
#1,252
of 2,799 outputs
Outputs of similar age
#236,965
of 423,960 outputs
Outputs of similar age from Brain and Behavior
#24
of 42 outputs
Altmetric has tracked 25,394,764 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,799 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one has gotten more attention than average, scoring higher than 52% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 423,960 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 42nd percentile – i.e., 42% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 42 others from the same source and published within six weeks on either side of this one. This one is in the 42nd percentile – i.e., 42% of its contemporaries scored the same or lower than it.