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Mendeley readers
Attention Score in Context
| Title |
Effective induction of high-titer antibodies by viral vector vaccines
|
|---|---|
| Published in |
Nature Medicine, July 2008
|
| DOI | 10.1038/nm.1850 |
| Pubmed ID | |
| Authors |
Simon J Draper, Anne C Moore, Anna L Goodman, Carole A Long, Anthony A Holder, Sarah C Gilbert, Fergal Hill, Adrian V S Hill |
| Abstract |
Protein-in-adjuvant vaccines have shown limited success against difficult diseases such as blood-stage malaria. Here we show that a recombinant adenovirus-poxvirus prime-boost immunization regime (known to induce strong T cell immunogenicity) can also induce very strong antigen-specific antibody responses, and we identify a simple complement-based adjuvant to further enhance immunogenicity. Antibodies induced against a blood-stage malaria antigen by this viral vector platform are highly effective against Plasmodium yoelii parasites in mice and against Plasmodium falciparum in vitro. |
Mendeley readers
The data shown below were compiled from readership statistics for 102 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 3 | 3% |
| South Africa | 1 | <1% |
| Brazil | 1 | <1% |
| Slovenia | 1 | <1% |
| Spain | 1 | <1% |
| Unknown | 95 | 93% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 29 | 28% |
| Student > Ph. D. Student | 18 | 18% |
| Student > Master | 11 | 11% |
| Student > Doctoral Student | 7 | 7% |
| Other | 7 | 7% |
| Other | 20 | 20% |
| Unknown | 10 | 10% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 29 | 28% |
| Immunology and Microbiology | 21 | 21% |
| Medicine and Dentistry | 17 | 17% |
| Biochemistry, Genetics and Molecular Biology | 9 | 9% |
| Social Sciences | 2 | 2% |
| Other | 9 | 9% |
| Unknown | 15 | 15% |
Attention Score in Context
This research output has an Altmetric Attention Score of 16. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 April 2022.
All research outputs
#1,879,476
of 22,712,476 outputs
Outputs from Nature Medicine
#3,251
of 8,464 outputs
Outputs of similar age
#4,971
of 81,934 outputs
Outputs of similar age from Nature Medicine
#11
of 44 outputs
Altmetric has tracked 22,712,476 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 8,464 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 96.7. This one has gotten more attention than average, scoring higher than 61% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 81,934 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 93% of its contemporaries.
We're also able to compare this research output to 44 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 75% of its contemporaries.