| Title |
Postural responses to electrical stimulation of the vestibular end organs in human subjects
|
|---|---|
| Published in |
Experimental Brain Research, June 2013
|
| DOI | 10.1007/s00221-013-3604-3 |
| Pubmed ID | |
| Authors |
Christopher Phillips, Christina DeFrancisci, Leo Ling, Kaibao Nie, Amy Nowack, James O. Phillips, Jay T. Rubinstein |
| Abstract |
A multichannel vestibular prosthesis that delivers electrical stimulation to the perilymph of individual semicircular canals is a potential new treatment modality for patients with vestibular deficiencies. Most research in this field has evaluated the efficacy of this approach by its ability to reproduce eye movements in response to head rotations. Our group has developed such a device and implanted it in four human subjects with intractable unilateral Meniere's disease. This allows us to evaluate individual semicircular canal contribution to the control of balance and posture in human subjects. In this report, we demonstrate that electrical stimulation trains delivered to the perilymph of individual semicircular canals elicit postural responses specific to the particular canal stimulated, with some current spread to adjacent end organs. Modulation of stimulation current modulates the amplitude of the postural response. However, eye movements elicited by the same electrical stimuli were not consistent with postural responses in magnitude or direction in all subjects. Taken together, these findings support the feasibility of a vestibular prosthesis for the control of balance and illustrate new challenges for the development of this technology. |
Mendeley readers
The data shown below were compiled from readership statistics for 55 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Korea, Republic of | 1 | 2% |
| Unknown | 54 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 12 | 22% |
| Student > Master | 9 | 16% |
| Student > Doctoral Student | 6 | 11% |
| Researcher | 5 | 9% |
| Student > Bachelor | 4 | 7% |
| Other | 10 | 18% |
| Unknown | 9 | 16% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 17 | 31% |
| Engineering | 11 | 20% |
| Neuroscience | 6 | 11% |
| Agricultural and Biological Sciences | 2 | 4% |
| Computer Science | 2 | 4% |
| Other | 7 | 13% |
| Unknown | 10 | 18% |
Attention Score in Context
This research output has an Altmetric Attention Score of 36. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 October 2015.
All research outputs
#936,734
of 22,712,476 outputs
Outputs from Experimental Brain Research
#56
of 3,218 outputs
Outputs of similar age
#8,115
of 197,681 outputs
Outputs of similar age from Experimental Brain Research
#3
of 50 outputs
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So far Altmetric has tracked 3,218 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.0. This one has done particularly well, scoring higher than 98% of its peers.
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