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Mendeley readers
Attention Score in Context
| Title |
Febrile temperatures can synchronize the growth of Plasmodium falciparum in vitro.
|
|---|---|
| Published in |
The Journal of Experimental Medicine, January 1989
|
| DOI | 10.1084/jem.169.1.357 |
| Pubmed ID | |
| Authors |
D Kwiatkowski |
| Abstract |
To investigate the possibility that the host fever response in malaria may affect parasite development, we studied the effect of temperature on Plasmodium falciparum in erythrocytic culture in vitro. Growth was markedly suppressed at 40 degrees C compared with 37 degrees C, due to disruption of the second half of the 48-h erythrocytic cycle. However, young intraerythrocytic parasites, which are highly exposed to fever during natural infection, appeared to develop normally at 40 degrees C. Because of the differential temperature sensitivity within the erythrocytic cycle, asynchronous cultures could be synchronized by transient elevations of temperature. Pronounced synchronization was observed when cultures were exposed to periodic elevations of temperature that simulated the 48-h fever cycle of tertian malaria. These findings indicate that malaria fever might act to promote parasite synchronization in vivo. |
Mendeley readers
The data shown below were compiled from readership statistics for 63 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 2% |
| Kenya | 1 | 2% |
| France | 1 | 2% |
| Tanzania, United Republic of | 1 | 2% |
| Unknown | 59 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 18 | 29% |
| Researcher | 14 | 22% |
| Student > Master | 6 | 10% |
| Student > Bachelor | 6 | 10% |
| Student > Doctoral Student | 4 | 6% |
| Other | 11 | 17% |
| Unknown | 4 | 6% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 28 | 44% |
| Biochemistry, Genetics and Molecular Biology | 10 | 16% |
| Medicine and Dentistry | 7 | 11% |
| Immunology and Microbiology | 5 | 8% |
| Computer Science | 2 | 3% |
| Other | 6 | 10% |
| Unknown | 5 | 8% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 July 2017.
All research outputs
#8,534,528
of 25,373,627 outputs
Outputs from The Journal of Experimental Medicine
#6,578
of 11,596 outputs
Outputs of similar age
#10,351
of 53,893 outputs
Outputs of similar age from The Journal of Experimental Medicine
#26
of 53 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 11,596 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.4. This one is in the 9th percentile – i.e., 9% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 53,893 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 21st percentile – i.e., 21% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 53 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.