Title |
Auto-titrating continuous positive airway pressure treatment for obstructive sleep apnoea after acute quadriplegia (COSAQ): study protocol for a randomized controlled trial
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Published in |
Trials, June 2013
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DOI | 10.1186/1745-6215-14-181 |
Pubmed ID | |
Authors |
David J Berlowitz, Najib Ayas, Maree Barnes, Douglas J Brown, Peter A Cistulli, Tim Geraghty, Alison Graham, Gerard A Kennedy, Bonsan Bonne Lee, Meg Morris, Fergal O’Donoghue, Peter D Rochford, Jack Ross, Balraj Singhal, Jo Spong, Brooke Wadsworth, Robert J Pierce |
Abstract |
Quadriplegia is a severe, catastrophic injury that predominantly affects people early in life, resulting in lifelong physical disability. Obstructive sleep apnoea is a direct consequence of quadriplegia and is associated with neurocognitive deficits, sleepiness and reduced quality of life. The usual treatment for sleep apnoea is nasal continuous positive airway pressure (CPAP); however, this is poorly tolerated in quadriplegia. To encourage patients to use this therapy, we have to demonstrate that the benefits outweigh the inconvenience. We therefore propose a prospective, multinational randomized controlled trial of three months of CPAP for obstructive sleep apnoea after acute quadriplegia. |
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Members of the public | 1 | 50% |
Mendeley readers
Geographical breakdown
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Unknown | 91 | 98% |
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