Title |
Heparin‐binding protein (HBP): an early marker of respiratory failure after trauma?
|
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Published in |
Acta Anaesthesiologica Scandinavica, January 2013
|
DOI | 10.1111/aas.12070 |
Pubmed ID | |
Authors |
J. JOHANSSON, O. BRATTSTRÖM, F. SJÖBERG, L. LINDBOM, H. HERWALD, E. WEITZBERG, A. OLDNER |
Abstract |
Trauma and its complications contribute to morbidity and mortality in the general population. Trauma victims are susceptible to acute respiratory distress syndrome (ARDS) and sepsis. Polymorphonuclear leucocytes (PMNs) are activated after trauma and there is substantial evidence of their involvement in the development of ARDS. Activated PMNs release heparin-binding protein (HBP), a granule protein previously shown to be involved in acute inflammatory reactions. We hypothesised that there is an increase in plasma HBP content after trauma and that the increased levels are related to the severity of the trauma or later development of severe sepsis and organ failure (ARDS). |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Australia | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 1 | 3% |
Romania | 1 | 3% |
Unknown | 31 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 6 | 18% |
Researcher | 5 | 15% |
Student > Master | 4 | 12% |
Lecturer | 2 | 6% |
Student > Bachelor | 2 | 6% |
Other | 9 | 27% |
Unknown | 5 | 15% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 21 | 64% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 6% |
Chemical Engineering | 1 | 3% |
Nursing and Health Professions | 1 | 3% |
Biochemistry, Genetics and Molecular Biology | 1 | 3% |
Other | 0 | 0% |
Unknown | 7 | 21% |