| Title |
Is complete surgical resection of stage 4 neuroblastoma a prerequisite for optimal survival or may >95 % tumour resection suffice?
|
|---|---|
| Published in |
Pediatric Surgery International, June 2012
|
| DOI | 10.1007/s00383-012-3109-3 |
| Pubmed ID | |
| Authors |
S. Zwaveling, G. A. M. Tytgat, D. C. van der Zee, M. H. W. A. Wijnen, H. A. Heij |
| Abstract |
Numerous studies have shown that for optimal survival in localized International Neuroblastoma Staging System stage 1-3 neuroblastoma, complete tumour resection (CR, macroscopic total tumour removal) is usually mandatory. In contrast, it is conceivable that in stage 4 disseminated disease, less extensive surgery [gross total resection (GTR), >95 % tumour removal] may suffice. This review shows substantial survival benefit in studies reporting on stage 4 patients undergoing CR, but also in studies reporting on patients undergoing GTR. Comparison between these studies is severely hampered by treatment heterogeneity. We found only four studies that explicitly compared survival between patients undergoing either CR or GTR. Two of these studies showed favourable results for patients treated with CR, while the other two did not show differences in survival. |
Mendeley readers
The data shown below were compiled from readership statistics for 41 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Netherlands | 1 | 2% |
| Unknown | 40 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Other | 6 | 15% |
| Researcher | 6 | 15% |
| Lecturer | 4 | 10% |
| Professor | 3 | 7% |
| Student > Ph. D. Student | 3 | 7% |
| Other | 10 | 24% |
| Unknown | 9 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 23 | 56% |
| Psychology | 2 | 5% |
| Computer Science | 1 | 2% |
| Neuroscience | 1 | 2% |
| Chemistry | 1 | 2% |
| Other | 0 | 0% |
| Unknown | 13 | 32% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 February 2013.
All research outputs
#20,195,024
of 22,712,476 outputs
Outputs from Pediatric Surgery International
#933
of 1,246 outputs
Outputs of similar age
#148,165
of 164,358 outputs
Outputs of similar age from Pediatric Surgery International
#8
of 9 outputs
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So far Altmetric has tracked 1,246 research outputs from this source. They receive a mean Attention Score of 2.4. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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We're also able to compare this research output to 9 others from the same source and published within six weeks on either side of this one.