Title |
Bacteria and cancer: cause, coincidence or cure? A review
|
---|---|
Published in |
Journal of Translational Medicine, March 2006
|
DOI | 10.1186/1479-5876-4-14 |
Pubmed ID | |
Authors |
DL Mager |
Abstract |
Research has found that certain bacteria are associated with human cancers. Their role, however, is still unclear. Convincing evidence links some species to carcinogenesis while others appear promising in the diagnosis, prevention or treatment of cancers. The complex relationship between bacteria and humans is demonstrated by Helicobacter pylori and Salmonella typhi infections. Research has shown that H. pylori can cause gastric cancer or MALT lymphoma in some individuals. In contrast, exposure to H. pylori appears to reduce the risk of esophageal cancer in others. Salmonella typhi infection has been associated with the development of gallbladder cancer; however S. typhi is a promising carrier of therapeutic agents for melanoma, colon and bladder cancers. Thus bacterial species and their roles in particular cancers appear to differ among different individuals. Many species, however, share an important characteristic: highly site-specific colonization. This critical factor may lead to the development of non-invasive diagnostic tests, innovative treatments and cancer vaccines. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 2 | 18% |
United Kingdom | 1 | 9% |
Colombia | 1 | 9% |
Canada | 1 | 9% |
United States | 1 | 9% |
Australia | 1 | 9% |
Unknown | 4 | 36% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 8 | 73% |
Practitioners (doctors, other healthcare professionals) | 2 | 18% |
Scientists | 1 | 9% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 3 | <1% |
Germany | 1 | <1% |
India | 1 | <1% |
Brazil | 1 | <1% |
Belgium | 1 | <1% |
Canada | 1 | <1% |
Unknown | 337 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 61 | 18% |
Student > Ph. D. Student | 60 | 17% |
Researcher | 46 | 13% |
Student > Master | 29 | 8% |
Student > Doctoral Student | 21 | 6% |
Other | 59 | 17% |
Unknown | 69 | 20% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 86 | 25% |
Biochemistry, Genetics and Molecular Biology | 66 | 19% |
Medicine and Dentistry | 45 | 13% |
Immunology and Microbiology | 23 | 7% |
Chemistry | 9 | 3% |
Other | 31 | 9% |
Unknown | 85 | 25% |