Title |
Genetic structure in four West African population groups
|
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Published in |
BMC Genomic Data, June 2005
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DOI | 10.1186/1471-2156-6-38 |
Pubmed ID | |
Authors |
Adebowale A Adeyemo, Guanjie Chen, Yuanxiu Chen, Charles Rotimi |
Abstract |
Africa contains the most genetically divergent group of continental populations and several studies have reported that African populations show a high degree of population stratification. In this regard, it is important to investigate the potential for population genetic structure or stratification in genetic epidemiology studies involving multiple African populations. The presences of genetic sub-structure, if not properly accounted for, have been reported to lead to spurious association between a putative risk allele and a disease. Within the context of the Africa America Diabetes Mellitus (AADM) Study (a genetic epidemiologic study of type 2 diabetes mellitus in West Africa), we have investigated population structure or stratification in four ethnic groups in two countries (Akan and Gaa-Adangbe from Ghana, Yoruba and Igbo from Nigeria) using data from 372 autosomal microsatellite loci typed in 493 unrelated persons (986 chromosomes). |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Nigeria | 7 | 25% |
United States | 2 | 7% |
Solomon Islands | 1 | 4% |
Switzerland | 1 | 4% |
Liberia | 1 | 4% |
Unknown | 16 | 57% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 25 | 89% |
Practitioners (doctors, other healthcare professionals) | 2 | 7% |
Scientists | 1 | 4% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
South Africa | 2 | 3% |
United States | 1 | 2% |
Ghana | 1 | 2% |
Brazil | 1 | 2% |
Unknown | 60 | 92% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 12 | 18% |
Researcher | 12 | 18% |
Student > Master | 6 | 9% |
Professor | 5 | 8% |
Student > Bachelor | 5 | 8% |
Other | 16 | 25% |
Unknown | 9 | 14% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 19 | 29% |
Biochemistry, Genetics and Molecular Biology | 12 | 18% |
Medicine and Dentistry | 8 | 12% |
Computer Science | 2 | 3% |
Arts and Humanities | 1 | 2% |
Other | 7 | 11% |
Unknown | 16 | 25% |