Title |
Polypharmacy, potentially inappropriate medication and cognitive status in Austrian nursing home residents: results from the OSiA study
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Published in |
Wiener Medizinische Wochenschrift, February 2016
|
DOI | 10.1007/s10354-015-0428-8 |
Pubmed ID | |
Authors |
Reinhard Alzner, Ulrike Bauer, Stefan Pitzer, Maria Magdalena Schreier, Jürgen Osterbrink, Bernhard Iglseder |
Abstract |
There is little research investigating polypharmacy and potentially inappropriate medications (PIM) in connection with cognitive status in residents of Austrian nursing homes. Our findings result from a cross-sectional survey of 425 residents (315 women, 110 men, mean 83.6 years) from 12 Austrian nursing homes. The number of systemically administered permanent prescription drugs was 8.99 ± 3.9 and decreased significantly with increasing cognitive impairment. Irrespective of cognitive status, polypharmacy (> 5 individual substances) was present in approximately 75 % of the residents. Hyper-polypharmacy (> 10 individual substances) was present among almost 50 % of the cognitively intact residents, and hence, significantly more frequent as compared with the group with the lowest cognitive performance (23.4 %). At least one PIM was found in 72.4 % of residents regardless of cognitive status. Predominantly, PIMs consisted of tranquilizers, antipsychotics, osmotic laxatives, non-steroidal anti-inflammatory drugs (NSAIDs) and anticholinergics, where only the number of NSAIDs decreased significantly with increasing cognitive impairment. In summary, our study shows a continued high prevalence of polypharmacy and PIM in long-term care institutions in Austria. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 5 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 1 | 20% |
Unknown | 4 | 80% |
Readers by discipline | Count | As % |
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Chemistry | 1 | 20% |
Medicine and Dentistry | 1 | 20% |
Unknown | 3 | 60% |