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Effectiveness and content analysis of interventions to enhance medication adherence and blood pressure control in hypertension: A systematic review and meta-analysis

Overview of attention for article published in Psychology & Health, January 2017
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  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (90th percentile)
  • Good Attention Score compared to outputs of the same age and source (78th percentile)

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Title
Effectiveness and content analysis of interventions to enhance medication adherence and blood pressure control in hypertension: A systematic review and meta-analysis
Published in
Psychology & Health, January 2017
DOI 10.1080/08870446.2016.1273356
Pubmed ID
Authors

Eimear C. Morrissey, Hannah Durand, Robby Nieuwlaat, Tamara Navarro, R. Brian Haynes, Jane C. Walsh, Gerard J. Molloy

Abstract

The objective of this systematic review is to evaluate the effectiveness of medication adherence interventions on blood pressure control in hypertensive patients. In addition, we aim to explore what barriers and facilitators in the interventions may have been targeted and how these might be related to the effect size on blood pressure (BP). This review is a hypertension-specific update to the previous Cochrane Review by Nieuwlaat et al. ( 2014 ) on interventions to enhance medication adherence. A systematic literature search was carried out and two authors independently screened titles and abstracts for their eligibility for inclusion and independently extracted data from the selected studies and assessed the methodological quality using the Cochrane Collaboration Risk of Bias Tool. A meta-analysis was conducted and additionally, theoretical factors in interventions were identified using the Theoretical Domains Framework. The meta-analysis found a modest main effect of adherence interventions on SBP (MD -2.71 mm Hg, 95% CI -4.17 to -1.26) and DBP (MD -1.25 mm Hg, 95% CI -1.72 to -.79). However, there was substantial significant heterogeneity across both outcomes. A narrative review on adherence outcomes was conducted. In terms of the theoretical analysis, the relationship between the total number of times the domains were coded within an intervention and change of SBP (r  =  -.234, p = .335) and DBP was not significant (r  =  -.080, p = .732). Similarly, the relationship between the total number of times different domains were coded within an intervention and change of SBP (r  =  .080, p = .746) and DBP was not significant (r  =  -.188, p = .415). This review and meta-analysis of interventions documented significant but modest post-intervention improvements in BP outcomes among hypertensive patients. However, this is a tentative finding as substantial heterogeneity and potential biases were present. One of the greatest challenges of this review was assessing risk of bias, extracting sufficient data to calculate effect size and coding interventions with the amount of information provided in papers. It is imperative that future adherence research comprehensively reports methodology.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 116 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 116 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 17 15%
Researcher 12 10%
Student > Ph. D. Student 11 9%
Student > Bachelor 7 6%
Other 7 6%
Other 18 16%
Unknown 44 38%
Readers by discipline Count As %
Medicine and Dentistry 22 19%
Nursing and Health Professions 13 11%
Psychology 12 10%
Social Sciences 4 3%
Business, Management and Accounting 3 3%
Other 14 12%
Unknown 48 41%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 18. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 August 2021.
All research outputs
#2,037,131
of 25,377,790 outputs
Outputs from Psychology & Health
#152
of 1,166 outputs
Outputs of similar age
#41,419
of 422,653 outputs
Outputs of similar age from Psychology & Health
#6
of 28 outputs
Altmetric has tracked 25,377,790 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,166 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.6. This one has done well, scoring higher than 86% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 422,653 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 28 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 78% of its contemporaries.