| Title |
Insulin resistance in type 1 diabetes: what is ‘double diabetes’ and what are the risks?
|
|---|---|
| Published in |
Diabetologia, April 2013
|
| DOI | 10.1007/s00125-013-2904-2 |
| Pubmed ID | |
| Authors |
S. J. Cleland, B. M. Fisher, H. M. Colhoun, N. Sattar, J. R. Petrie |
| Abstract |
In this review, we explore the concept of 'double diabetes', a combination of type 1 diabetes with features of insulin resistance and type 2 diabetes. After considering whether double diabetes is a useful concept, we discuss potential mechanisms of increased insulin resistance in type 1 diabetes before examining the extent to which double diabetes might increase the risk of cardiovascular disease (CVD). We then go on to consider the proposal that weight gain from intensive insulin regimens may be associated with increased CV risk factors in some patients with type 1 diabetes, and explore the complex relationships between weight gain, insulin resistance, glycaemic control and CV outcome. Important comparisons and contrasts between type 1 diabetes and type 2 diabetes are highlighted in terms of hepatic fat, fat partitioning and lipid profile, and how these may differ between type 1 diabetic patients with and without double diabetes. In so doing, we hope this work will stimulate much-needed research in this area and an improvement in clinical practice. |
X Demographics
The data shown below were collected from the profiles of 52 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 11 | 21% |
| United Kingdom | 8 | 15% |
| Spain | 3 | 6% |
| Australia | 2 | 4% |
| Germany | 2 | 4% |
| Canada | 2 | 4% |
| Netherlands | 2 | 4% |
| Poland | 2 | 4% |
| Malta | 1 | 2% |
| Other | 4 | 8% |
| Unknown | 15 | 29% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 40 | 77% |
| Practitioners (doctors, other healthcare professionals) | 8 | 15% |
| Scientists | 3 | 6% |
| Science communicators (journalists, bloggers, editors) | 1 | 2% |
Mendeley readers
The data shown below were compiled from readership statistics for 239 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Mexico | 3 | 1% |
| United Kingdom | 2 | <1% |
| United States | 2 | <1% |
| Ghana | 1 | <1% |
| South Africa | 1 | <1% |
| Canada | 1 | <1% |
| France | 1 | <1% |
| Japan | 1 | <1% |
| Colombia | 1 | <1% |
| Other | 0 | 0% |
| Unknown | 226 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 43 | 18% |
| Student > Postgraduate | 27 | 11% |
| Student > Ph. D. Student | 21 | 9% |
| Researcher | 19 | 8% |
| Student > Bachelor | 19 | 8% |
| Other | 48 | 20% |
| Unknown | 62 | 26% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 101 | 42% |
| Biochemistry, Genetics and Molecular Biology | 14 | 6% |
| Agricultural and Biological Sciences | 13 | 5% |
| Nursing and Health Professions | 12 | 5% |
| Pharmacology, Toxicology and Pharmaceutical Science | 6 | 3% |
| Other | 28 | 12% |
| Unknown | 65 | 27% |
Attention Score in Context
This research output has an Altmetric Attention Score of 58. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 September 2022.
All research outputs
#749,327
of 26,017,215 outputs
Outputs from Diabetologia
#386
of 5,621 outputs
Outputs of similar age
#5,152
of 208,612 outputs
Outputs of similar age from Diabetologia
#2
of 51 outputs
Altmetric has tracked 26,017,215 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 5,621 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 24.1. This one has done particularly well, scoring higher than 91% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 208,612 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 51 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 96% of its contemporaries.