| Title |
Centrioles: active players or passengers during mitosis?
|
|---|---|
| Published in |
Cellular and Molecular Life Sciences, March 2010
|
| DOI | 10.1007/s00018-010-0323-9 |
| Pubmed ID | |
| Authors |
Alain Debec, William Sullivan, Monica Bettencourt-Dias |
| Abstract |
Centrioles are cylinders made of nine microtubule (MT) triplets present in many eukaryotes. Early studies, where centrosomes were seen at the poles of the mitotic spindle led to their coining as "the organ for cell division". However, a variety of subsequent observational and functional studies showed that centrosomes might not always be essential for mitosis. Here we review the arguments in this debate. We describe the centriole structure and its distribution in the eukaryotic tree of life and clarify its role in the organization of the centrosome and cilia, with an historical perspective. An important aspect of the debate addressed in this review is how centrioles are inherited and the role of the spindle in this process. In particular, germline inheritance of centrosomes, such as their de novo formation in parthenogenetic species, poses many interesting questions. We finish by discussing the most likely functions of centrioles and laying out new research avenues. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 212 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 4 | 2% |
| United States | 2 | <1% |
| Switzerland | 2 | <1% |
| Finland | 1 | <1% |
| France | 1 | <1% |
| Portugal | 1 | <1% |
| Russia | 1 | <1% |
| Denmark | 1 | <1% |
| Japan | 1 | <1% |
| Other | 1 | <1% |
| Unknown | 197 | 93% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 57 | 27% |
| Student > Ph. D. Student | 54 | 25% |
| Student > Master | 22 | 10% |
| Student > Bachelor | 18 | 8% |
| Student > Doctoral Student | 9 | 4% |
| Other | 28 | 13% |
| Unknown | 24 | 11% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 118 | 56% |
| Biochemistry, Genetics and Molecular Biology | 52 | 25% |
| Medicine and Dentistry | 5 | 2% |
| Physics and Astronomy | 4 | 2% |
| Chemistry | 3 | 1% |
| Other | 6 | 3% |
| Unknown | 24 | 11% |
Attention Score in Context
This research output has an Altmetric Attention Score of 14. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 October 2021.
All research outputs
#2,358,960
of 23,794,258 outputs
Outputs from Cellular and Molecular Life Sciences
#305
of 4,151 outputs
Outputs of similar age
#8,816
of 96,260 outputs
Outputs of similar age from Cellular and Molecular Life Sciences
#1
of 26 outputs
Altmetric has tracked 23,794,258 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,151 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.0. This one has done particularly well, scoring higher than 99% of its peers.
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We're also able to compare this research output to 26 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 96% of its contemporaries.