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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Some Synonymous and Nonsynonymous gyrA Mutations in Mycobacterium tuberculosis Lead to Systematic False-Positive Fluoroquinolone Resistance Results with the Hain GenoType MTBDRsl Assays
|
|---|---|
| Published in |
Antimicrobial Agents and Chemotherapy, March 2017
|
| DOI | 10.1128/aac.02169-16 |
| Pubmed ID | |
| Authors |
Adebisi Ajileye, Nataly Alvarez, Matthias Merker, Timothy M. Walker, Suriya Akter, Kerstin Brown, Danesh Moradigaravand, Thomas Schön, Sönke Andres, Viola Schleusener, Shaheed V. Omar, Francesc Coll, Hairong Huang, Roland Diel, Nazir Ismail, Julian Parkhill, Bouke C. de Jong, Tim E. A. Peto, Derrick W. Crook, Stefan Niemann, Jaime Robledo, E. Grace Smith, Sharon J. Peacock, Claudio U. Köser |
| Abstract |
We demonstrated that some non-synonymous and synonymous mutations in gyrA in Mycobacterium tuberculosis result in systematic false-resistance results to fluoroquinolones using the Hain GenoType MTBDRsl assays (version 1 and 2) by preventing the binding of wild-type probes. Moreover, such mutations can prevent the binding of mutant probes, designed for the identification of specific resistance mutations. Although these mutations are likely rare globally, they occur in approximately 7% of multidrug-resistant tuberculosis strains in some settings. |
X Demographics
The data shown below were collected from the profiles of 9 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Denmark | 1 | 11% |
| Venezuela, Bolivarian Republic of | 1 | 11% |
| Brazil | 1 | 11% |
| Unknown | 6 | 67% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 6 | 67% |
| Scientists | 3 | 33% |
Mendeley readers
The data shown below were compiled from readership statistics for 91 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 91 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 15 | 16% |
| Researcher | 13 | 14% |
| Other | 9 | 10% |
| Student > Ph. D. Student | 9 | 10% |
| Student > Bachelor | 6 | 7% |
| Other | 16 | 18% |
| Unknown | 23 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 18 | 20% |
| Medicine and Dentistry | 18 | 20% |
| Agricultural and Biological Sciences | 12 | 13% |
| Immunology and Microbiology | 6 | 7% |
| Computer Science | 2 | 2% |
| Other | 6 | 7% |
| Unknown | 29 | 32% |
Attention Score in Context
This research output has an Altmetric Attention Score of 17. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 May 2022.
All research outputs
#2,191,669
of 25,382,440 outputs
Outputs from Antimicrobial Agents and Chemotherapy
#1,012
of 15,580 outputs
Outputs of similar age
#40,791
of 322,886 outputs
Outputs of similar age from Antimicrobial Agents and Chemotherapy
#47
of 245 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 15,580 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.2. This one has done particularly well, scoring higher than 93% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 322,886 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 87% of its contemporaries.
We're also able to compare this research output to 245 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 80% of its contemporaries.