| Title |
Multicenter European Prevalence Study of Neurocognitive Impairment and Associated Factors in HIV Positive Patients
|
|---|---|
| Published in |
AIDS and Behavior, January 2017
|
| DOI | 10.1007/s10461-017-1683-z |
| Pubmed ID | |
| Authors |
Lewis J. Haddow, Rosanna Laverick, Marina Daskalopoulou, Jeffrey McDonnell, Fiona C. Lampe, Richard Gilson, Andrew Speakman, Andrea Antinori, Pietro Balestra, Tina Bruun, Jan Gerstoft, Lars Nielsen, Anna Vassilenko, Simon Collins, Alison J. Rodger, For the Cognitive Impairment in People with HIV in the European Region (CIPHER) Study Group |
| Abstract |
We conducted a cross-sectional study in 448 HIV positive patients attending five European outpatient clinics to determine prevalence of and factors associated with neurocognitive impairment (NCI) using computerized and pen-and-paper neuropsychological tests. NCI was defined as a normalized Z score ≤-1 in at least 2 out of 5 cognitive domains. Participants' mean age was 45.8 years; 84% male; 87% white; 56% university educated; median CD4 count 550 cells/mm(3); 89% on antiretroviral therapy. 156 (35%) participants had NCI, among whom 26 (17%; 5.8% overall) reported a decline in activities of daily living. Prevalence of NCI was lower in those always able to afford basic needs (adjusted prevalence ratio [aPR] 0.71, 95% confidence interval [CI] 0.54-0.94) or with a university education (aPR 0.72, 95% CI 0.54-0.97) and higher in those with severe depressive symptoms (aPR 1.53, 95% CI 1.09-2.14) or a significant comorbid condition (aPR 1.40, 95% CI 1.03-1.90). |
X Demographics
The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 3 | 43% |
| United States | 2 | 29% |
| Unknown | 2 | 29% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 7 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 101 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 101 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 22 | 22% |
| Student > Ph. D. Student | 11 | 11% |
| Student > Bachelor | 9 | 9% |
| Researcher | 8 | 8% |
| Student > Doctoral Student | 6 | 6% |
| Other | 10 | 10% |
| Unknown | 35 | 35% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 16 | 16% |
| Psychology | 13 | 13% |
| Nursing and Health Professions | 11 | 11% |
| Neuroscience | 7 | 7% |
| Agricultural and Biological Sciences | 3 | 3% |
| Other | 12 | 12% |
| Unknown | 39 | 39% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 April 2018.
All research outputs
#7,866,480
of 23,849,058 outputs
Outputs from AIDS and Behavior
#1,389
of 3,566 outputs
Outputs of similar age
#145,820
of 424,088 outputs
Outputs of similar age from AIDS and Behavior
#37
of 106 outputs
Altmetric has tracked 23,849,058 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,566 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.0. This one has gotten more attention than average, scoring higher than 55% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 424,088 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 53% of its contemporaries.
We're also able to compare this research output to 106 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 63% of its contemporaries.