| Title |
Agammaglobulinemia and lack of immunization protection in exudative atopic dermatitis
|
|---|---|
| Published in |
European Journal of Pediatrics, April 2013
|
| DOI | 10.1007/s00431-013-2011-x |
| Pubmed ID | |
| Authors |
Petra Lankisch, Hans-Jürgen Laws, Michael Weiss, Arndt Borkhardt |
| Abstract |
Atopic dermatitis is very frequent in the first 6 months of life, and the severe exudative form of this skin disorder is by no means rare. Failure to achieve immunization protection is a potentially life-threatening complication of exudative atopic dermatitis that may go unrecognized. We report the case of a 6-month-old infant with severe exudative atopic dermatitis in whom hypoproteinemia and agammaglobulinemia were attributed to the massive exudation after exclusion of other possible causes. The patient failed to respond to standard immunization, and adequate protection with a good antibody response could be achieved only after exudation from the skin lesions had been treated by intensive topical skin therapy and multiple intravenous immunoglobulin substitution. Two otherwise similar earlier case reports did not investigate the immune status. Therefore, to the best of our knowledge, this is the first report to draw attention to absence of immunization protection in exudative atopic dermatitis. Conclusion: We hope that our case report will motivate pediatricians to check the immunization status of patients with exudative atopic dermatitis and take the necessary steps to improve their care. |
Mendeley readers
The data shown below were compiled from readership statistics for 8 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 8 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 2 | 25% |
| Student > Master | 2 | 25% |
| Researcher | 1 | 13% |
| Student > Bachelor | 1 | 13% |
| Unknown | 2 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 4 | 50% |
| Psychology | 1 | 13% |
| Agricultural and Biological Sciences | 1 | 13% |
| Unknown | 2 | 25% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 April 2013.
All research outputs
#20,196,270
of 22,714,025 outputs
Outputs from European Journal of Pediatrics
#3,419
of 3,673 outputs
Outputs of similar age
#167,999
of 193,059 outputs
Outputs of similar age from European Journal of Pediatrics
#45
of 51 outputs
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