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A defense of using resting-state fMRI as null data for estimating false positive rates

Overview of attention for article published in Cognitive Neuroscience, February 2017
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Title
A defense of using resting-state fMRI as null data for estimating false positive rates
Published in
Cognitive Neuroscience, February 2017
DOI 10.1080/17588928.2017.1287069
Pubmed ID
Authors

Thomas E. Nichols, Anders Eklund, Hans Knutsson

Abstract

A recent Editorial by Slotnick (2017) reconsiders the findings of our paper on the accuracy of false positive rate control with cluster inference in fMRI (Eklund et al, 2016), in particular criticising our use of resting state fMRI data as a source for null data in the evaluation of task fMRI methods. We defend this use of resting fMRI data, as while there is much structure in this data, we argue it is representative of task data noise and such analysis software should be able to accommodate this noise. We also discuss a potential problem with Slotnick's own method.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 32 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 1 3%
Canada 1 3%
Unknown 30 94%

Demographic breakdown

Readers by professional status Count As %
Researcher 9 28%
Student > Ph. D. Student 5 16%
Student > Master 4 13%
Student > Bachelor 3 9%
Student > Doctoral Student 3 9%
Other 4 13%
Unknown 4 13%
Readers by discipline Count As %
Psychology 8 25%
Neuroscience 5 16%
Medicine and Dentistry 4 13%
Mathematics 3 9%
Agricultural and Biological Sciences 2 6%
Other 4 13%
Unknown 6 19%