↓ Skip to main content

Recruited brown adipose tissue as an antiobesity agent in humans

Overview of attention for article published in Journal of Clinical Investigation, July 2013
Altmetric Badge

About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (99th percentile)
  • High Attention Score compared to outputs of the same age and source (99th percentile)

Citations

dimensions_citation
787 Dimensions

Readers on

mendeley
597 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Recruited brown adipose tissue as an antiobesity agent in humans
Published in
Journal of Clinical Investigation, July 2013
DOI 10.1172/jci67803
Pubmed ID
Authors

Takeshi Yoneshiro, Sayuri Aita, Mami Matsushita, Takashi Kayahara, Toshimitsu Kameya, Yuko Kawai, Toshihiko Iwanaga, Masayuki Saito

Abstract

Brown adipose tissue (BAT) burns fat to produce heat when the body is exposed to cold and plays a role in energy metabolism. Using fluorodeoxyglucose-positron emission tomography and computed tomography, we previously reported that BAT decreases with age and thereby accelerates age-related accumulation of body fat in humans. Thus, the recruitment of BAT may be effective for body fat reduction. In this study, we examined the effects of repeated stimulation by cold and capsinoids (nonpungent capsaicin analogs) in healthy human subjects with low BAT activity. Acute cold exposure at 19°C for 2 hours increased energy expenditure (EE). Cold-induced increments of EE (CIT) strongly correlated with BAT activity independently of age and fat-free mass. Daily 2-hour cold exposure at 17°C for 6 weeks resulted in a parallel increase in BAT activity and CIT and a concomitant decrease in body fat mass. Changes in BAT activity and body fat mass were negatively correlated. Similarly, daily ingestion of capsinoids for 6 weeks increased CIT. These results demonstrate that human BAT can be recruited even in individuals with decreased BAT activity, thereby contributing to body fat reduction.

X Demographics

X Demographics

The data shown below were collected from the profiles of 37 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 597 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 4 <1%
Germany 2 <1%
Japan 2 <1%
Canada 1 <1%
Mexico 1 <1%
United Kingdom 1 <1%
Spain 1 <1%
Brazil 1 <1%
China 1 <1%
Other 1 <1%
Unknown 582 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 101 17%
Student > Master 83 14%
Researcher 72 12%
Student > Bachelor 71 12%
Student > Doctoral Student 35 6%
Other 105 18%
Unknown 130 22%
Readers by discipline Count As %
Agricultural and Biological Sciences 121 20%
Medicine and Dentistry 115 19%
Biochemistry, Genetics and Molecular Biology 96 16%
Nursing and Health Professions 18 3%
Sports and Recreations 15 3%
Other 81 14%
Unknown 151 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 277. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 March 2024.
All research outputs
#129,967
of 25,540,105 outputs
Outputs from Journal of Clinical Investigation
#129
of 17,245 outputs
Outputs of similar age
#784
of 207,113 outputs
Outputs of similar age from Journal of Clinical Investigation
#2
of 124 outputs
Altmetric has tracked 25,540,105 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 17,245 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 16.7. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 207,113 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 124 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 99% of its contemporaries.