| Title |
Stress, loneliness, and changes in herpesvirus latency
|
|---|---|
| Published in |
Journal of Behavioral Medicine, September 1985
|
| DOI | 10.1007/bf00870312 |
| Pubmed ID | |
| Authors |
Ronald Glaser, Janice K. Kiecolt-Glaser, Carl E. Speicher, Jane E. Holliday |
| Abstract |
This study used a prospective design to examine the influence of examination stress and loneliness on herpesvirus latency as measured by changes in antibody levels to three herpesviruses, Epstein-Barr virus (EBV), Herpes simplex type I (HSV-1), and cytomegalovirus (CMV). Three blood samples were obtained from 49 first-year medical students, with the first sample drawn 1 month before final examinations, the second on the first day of final examinations, and the third during the first week after their return from summer vacation. A median split on the UCLA Loneliness Scale divided subjects into high- and low-scoring loneliness groups. There were significant changes in the antibody titers to all three herpesviruses across the sample points, with the lowest levels found in the third (low stress) sample. High-loneliness subjects had significantly higher EBV antibody titers than low-loneliness subjects. These data suggest that stress-related immunosuppression can significantly modulate herpesvirus latency. |
Mendeley readers
The data shown below were compiled from readership statistics for 141 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 2% |
| Portugal | 1 | <1% |
| Unknown | 137 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 29 | 21% |
| Student > Bachelor | 24 | 17% |
| Student > Master | 13 | 9% |
| Researcher | 11 | 8% |
| Student > Doctoral Student | 8 | 6% |
| Other | 24 | 17% |
| Unknown | 32 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Psychology | 43 | 30% |
| Agricultural and Biological Sciences | 15 | 11% |
| Medicine and Dentistry | 14 | 10% |
| Social Sciences | 10 | 7% |
| Biochemistry, Genetics and Molecular Biology | 6 | 4% |
| Other | 20 | 14% |
| Unknown | 33 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 16. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 February 2017.
All research outputs
#1,903,658
of 22,953,506 outputs
Outputs from Journal of Behavioral Medicine
#162
of 1,077 outputs
Outputs of similar age
#192
of 9,911 outputs
Outputs of similar age from Journal of Behavioral Medicine
#1
of 4 outputs
Altmetric has tracked 22,953,506 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,077 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 14.7. This one has done well, scoring higher than 84% of its peers.
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We're also able to compare this research output to 4 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them