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Cigarette smoking and DNA methylation

Overview of attention for article published in Frontiers in Genetics, January 2013
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (98th percentile)
  • High Attention Score compared to outputs of the same age and source (98th percentile)

Mentioned by

news
3 news outlets
blogs
4 blogs
twitter
8 X users
peer_reviews
1 peer review site
facebook
1 Facebook page
wikipedia
2 Wikipedia pages

Citations

dimensions_citation
333 Dimensions

Readers on

mendeley
331 Mendeley
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Title
Cigarette smoking and DNA methylation
Published in
Frontiers in Genetics, January 2013
DOI 10.3389/fgene.2013.00132
Pubmed ID
Authors

Ken W. K. Lee, Zdenka Pausova

Abstract

DNA methylation is the most studied epigenetic modification, capable of controlling gene expression in the contexts of normal traits or diseases. It is highly dynamic during early embryogenesis and remains relatively stable throughout life, and such patterns are intricately related to human development. DNA methylation is a quantitative trait determined by a complex interplay of genetic and environmental factors. Genetic variants at a specific locus can influence both regional and distant DNA methylation. The environment can have varying effects on DNA methylation depending on when the exposure occurs, such as during prenatal life or during adulthood. In particular, cigarette smoking in the context of both current smoking and prenatal exposure is a strong modifier of DNA methylation. Epigenome-wide association studies have uncovered candidate genes associated with cigarette smoking that have biologically relevant functions in the etiology of smoking-related diseases. As such, DNA methylation is a potential mechanistic link between current smoking and cancer, as well as prenatal cigarette-smoke exposure and the development of adult chronic diseases.

X Demographics

X Demographics

The data shown below were collected from the profiles of 8 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 331 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 2 <1%
United Kingdom 2 <1%
Czechia 1 <1%
Sweden 1 <1%
Canada 1 <1%
United States 1 <1%
Unknown 323 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 66 20%
Student > Master 52 16%
Researcher 50 15%
Student > Bachelor 48 15%
Student > Doctoral Student 13 4%
Other 42 13%
Unknown 60 18%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 73 22%
Medicine and Dentistry 65 20%
Agricultural and Biological Sciences 61 18%
Neuroscience 8 2%
Social Sciences 6 2%
Other 41 12%
Unknown 77 23%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 58. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 December 2023.
All research outputs
#736,129
of 25,403,829 outputs
Outputs from Frontiers in Genetics
#113
of 13,705 outputs
Outputs of similar age
#5,431
of 289,094 outputs
Outputs of similar age from Frontiers in Genetics
#5
of 318 outputs
Altmetric has tracked 25,403,829 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 13,705 research outputs from this source. They receive a mean Attention Score of 3.8. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 289,094 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 318 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 98% of its contemporaries.