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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Marker-free plasmids for biotechnological applications – implications and perspectives
|
|---|---|
| Published in |
Trends in Biotechnology, July 2013
|
| DOI | 10.1016/j.tibtech.2013.06.001 |
| Pubmed ID | |
| Authors |
Pedro H. Oliveira, Juergen Mairhofer |
| Abstract |
Nonviral gene therapy and DNA vaccines have become the first promising approaches to treat, cure, or ultimately prevent disease by providing genetic information encoded on a plasmid. Since 1989, more than 1800 clinical trials have been approved worldwide, and approximately 20% of them are using plasmid DNA (pDNA) as a vector system. Although much safer than viral approaches, DNA vectors generally do encode antibiotic resistance genes in the plasmid backbone. These antibiotic resistance markers constitute a possible safety risk, and they are associated with structural plasmid instabilities and decreased gene delivery efficiency. These drawbacks have initiated the development of various antibiotic marker-free selection approaches. We provide an overview on the potential implications of marker-free plasmids and perspectives for their successful biotechnological use in the future. |
X Demographics
The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 40% |
| Austria | 1 | 20% |
| Unknown | 2 | 40% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 60% |
| Science communicators (journalists, bloggers, editors) | 2 | 40% |
Mendeley readers
The data shown below were compiled from readership statistics for 169 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 2% |
| France | 2 | 1% |
| Pakistan | 1 | <1% |
| Ireland | 1 | <1% |
| Portugal | 1 | <1% |
| Kenya | 1 | <1% |
| Austria | 1 | <1% |
| Egypt | 1 | <1% |
| United Kingdom | 1 | <1% |
| Other | 0 | 0% |
| Unknown | 157 | 93% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 37 | 22% |
| Student > Ph. D. Student | 30 | 18% |
| Student > Master | 29 | 17% |
| Student > Bachelor | 25 | 15% |
| Student > Doctoral Student | 6 | 4% |
| Other | 27 | 16% |
| Unknown | 15 | 9% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 78 | 46% |
| Biochemistry, Genetics and Molecular Biology | 40 | 24% |
| Medicine and Dentistry | 6 | 4% |
| Engineering | 5 | 3% |
| Chemistry | 4 | 2% |
| Other | 19 | 11% |
| Unknown | 17 | 10% |
Attention Score in Context
This research output has an Altmetric Attention Score of 23. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 September 2023.
All research outputs
#1,645,956
of 25,374,917 outputs
Outputs from Trends in Biotechnology
#200
of 2,856 outputs
Outputs of similar age
#13,756
of 206,393 outputs
Outputs of similar age from Trends in Biotechnology
#2
of 23 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,856 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.5. This one has done particularly well, scoring higher than 92% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 206,393 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 93% of its contemporaries.
We're also able to compare this research output to 23 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 91% of its contemporaries.