Title |
Adding Epoetin Alfa to Intense Dose-Dense Adjuvant Chemotherapy for Breast Cancer: Randomized Clinical Trial
|
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Published in |
JNCI: Journal of the National Cancer Institute, July 2013
|
DOI | 10.1093/jnci/djt145 |
Pubmed ID | |
Authors |
Volker Moebus, Christian Jackisch, Andreas Schneeweiss, Jens Huober, Hans-Joachim Lueck, Andreas du Bois, Christoph Thomssen, Christian Kurbacher, Walther Kuhn, Ulrike Nitz, Ingo B. Runnebaum, Axel Hinke, Rolf Kreienberg, Michael Untch |
Abstract |
The AGO-ETC trial compared 5-year relapse-free survival of intense dose-dense (IDD) sequential chemotherapy with epirubicin (E), paclitaxel (T), and cyclophosphamide (C) (IDD-ETC) every 2 weeks vs conventional scheduled epirubicin/cyclophosphamide followed by paclitaxel (EC→T) (every 3 weeks) as adjuvant treatment in high-risk breast cancer patients. The objective of this study was to evaluate the safety and efficacy of epoetin alfa in a second randomization of the intense dose-dense arm. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 50% |
Belgium | 1 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Spain | 1 | 1% |
United States | 1 | 1% |
Ecuador | 1 | 1% |
Unknown | 75 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
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Other | 11 | 14% |
Researcher | 10 | 13% |
Student > Bachelor | 10 | 13% |
Student > Master | 6 | 8% |
Lecturer | 3 | 4% |
Other | 14 | 18% |
Unknown | 24 | 31% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 31 | 40% |
Nursing and Health Professions | 8 | 10% |
Biochemistry, Genetics and Molecular Biology | 3 | 4% |
Agricultural and Biological Sciences | 3 | 4% |
Psychology | 2 | 3% |
Other | 5 | 6% |
Unknown | 26 | 33% |