Title |
The protective effect of recombinant Lactococcus lactis oral vaccine on a Clostridium difficile-infected animal model
|
---|---|
Published in |
BMC Gastroenterology, July 2013
|
DOI | 10.1186/1471-230x-13-117 |
Pubmed ID | |
Authors |
Xiao-qiang Yang, Ya-gang Zhao, Xue-qing Chen, Bo Jiang, Da-yong Sun |
Abstract |
Oral immunization with vaccines may be an effective strategy for prevention of Clostridium difficile infection (CDI). However, application of previously developed vaccines for preventing CDI has been limited due to various reasons. Here, we developed a recombinant Lactococcus lactis oral vaccine and evaluated its effect on a C. difficile-infected animal model established in golden hamsters in attempt to provide an alternative strategy for CDI prevention. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 47 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 47 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 9 | 19% |
Student > Master | 6 | 13% |
Student > Ph. D. Student | 4 | 9% |
Other | 3 | 6% |
Student > Bachelor | 3 | 6% |
Other | 11 | 23% |
Unknown | 11 | 23% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 11 | 23% |
Medicine and Dentistry | 9 | 19% |
Immunology and Microbiology | 5 | 11% |
Biochemistry, Genetics and Molecular Biology | 3 | 6% |
Social Sciences | 3 | 6% |
Other | 3 | 6% |
Unknown | 13 | 28% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 July 2013.
All research outputs
#18,341,711
of 22,714,025 outputs
Outputs from BMC Gastroenterology
#1,131
of 1,731 outputs
Outputs of similar age
#128,818
of 172,131 outputs
Outputs of similar age from BMC Gastroenterology
#11
of 19 outputs
Altmetric has tracked 22,714,025 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,731 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.0. This one is in the 21st percentile – i.e., 21% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 172,131 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 19 others from the same source and published within six weeks on either side of this one. This one is in the 10th percentile – i.e., 10% of its contemporaries scored the same or lower than it.