| Title |
Reversible states of physical and/or cognitive dysfunction: A 9-year longitudinal study
|
|---|---|
| Published in |
The journal of nutrition, health & aging, March 2017
|
| DOI | 10.1007/s12603-017-0878-3 |
| Pubmed ID | |
| Authors |
Clifford Qualls, D.L. Waters, B. Vellas, D.T. Villareal, P.J. Garry, A. Gallini, S. Andrieu |
| Abstract |
To determine 1) age-adjusted transition probabilities to worsening physical/cognitive function states, reversal to normal cognition/physical function, or maintenance of normal state; 2) whether these transitions are modulated by sex, BMI, education, hypertension (HTN), health status, or APOE4; 3) whether worsening gait speed preceded cognition change, or vice versa. Analysis of 9-year prospective cohort data from the New Mexico Aging Process Study. Healthy independent-living adults. 60+ years of age (n= 598). Gait speed, cognitive function (3MSE score), APOE4, HTN, BMI, education, health status. Over 9 years, 2129 one-year transitions were observed. 32.6% stayed in the same state, while gait speed and cognitive function (3MSE scores) improved for 38% and 43% of participants per year, respectively. Transitions to improved function decreased with age (P< 0.001), APOE4 status (P=0.02), BMI (P=0.009), and health status (P=0.009). Transitions to worse function were significantly increased for the same factors (all P<0.05). Times to lower gait speed and cognitive function did not precede each other (P=0.91). Transitions in gait speed and cognition were mutable with substantial likelihood of transition to improvement in physical and cognitive function even in oldest-old, which may have clinical implications for treatment interventions. |
X Demographics
The data shown below were collected from the profiles of 25 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Australia | 4 | 16% |
| United States | 3 | 12% |
| Brazil | 2 | 8% |
| France | 2 | 8% |
| Spain | 2 | 8% |
| Canada | 2 | 8% |
| United Kingdom | 1 | 4% |
| Unknown | 9 | 36% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 15 | 60% |
| Members of the public | 9 | 36% |
| Practitioners (doctors, other healthcare professionals) | 1 | 4% |
Mendeley readers
The data shown below were compiled from readership statistics for 77 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 77 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 15 | 19% |
| Student > Master | 13 | 17% |
| Student > Bachelor | 8 | 10% |
| Student > Doctoral Student | 6 | 8% |
| Researcher | 6 | 8% |
| Other | 13 | 17% |
| Unknown | 16 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 14 | 18% |
| Sports and Recreations | 10 | 13% |
| Psychology | 8 | 10% |
| Nursing and Health Professions | 5 | 6% |
| Neuroscience | 4 | 5% |
| Other | 6 | 8% |
| Unknown | 30 | 39% |
Attention Score in Context
This research output has an Altmetric Attention Score of 13. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 January 2019.
All research outputs
#2,768,520
of 25,728,855 outputs
Outputs from The journal of nutrition, health & aging
#347
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Outputs of similar age
#49,899
of 325,363 outputs
Outputs of similar age from The journal of nutrition, health & aging
#7
of 35 outputs
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We're also able to compare this research output to 35 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 80% of its contemporaries.