| Title |
Obesity, cardiovascular disease, and role of vitamin C on inflammation: a review of facts and underlying mechanisms
|
|---|---|
| Published in |
Inflammopharmacology, February 2017
|
| DOI | 10.1007/s10787-017-0314-7 |
| Pubmed ID | |
| Authors |
Mohammed S. Ellulu |
| Abstract |
Obesity means the accumulation of excessive fat that may interfere with the maintenance of optimal state of health. Obesity causes cardiac and vascular disease through well-known mediators such as hypertension, type-2 diabetes mellitus, and dyslipidemia, but there are evidences for other mediators such as chronic inflammation, oxidative stress, and thrombosis. The decreased levels of antioxidants factors and nitric oxide predispose to further cardiovascular adverse events. To reduce the risks, antioxidants can help by neutralizing the free radicals and protecting from damage by donating electrons. Having the capacity, vitamin C protects from oxidative stress, prevention of non-enzymatic glycosylation of proteins, and enhances arterial dilation through its effect on nitric oxide release. It also decreases lipid peroxidation, and alleviates inflammation. The anti-inflammatory property of vitamin C could be attributed to ability to modulate the NF-kB DNA binding activity and down-regulation in the hepatic mRNA expression for the interleukins and tumor factors. |
X Demographics
The data shown below were collected from the profiles of 28 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 10 | 36% |
| El Salvador | 1 | 4% |
| Dominican Republic | 1 | 4% |
| Ecuador | 1 | 4% |
| Chile | 1 | 4% |
| Argentina | 1 | 4% |
| Unknown | 13 | 46% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 20 | 71% |
| Practitioners (doctors, other healthcare professionals) | 7 | 25% |
| Scientists | 1 | 4% |
Mendeley readers
The data shown below were compiled from readership statistics for 128 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 128 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 16 | 13% |
| Student > Master | 13 | 10% |
| Student > Ph. D. Student | 10 | 8% |
| Researcher | 8 | 6% |
| Student > Doctoral Student | 7 | 5% |
| Other | 24 | 19% |
| Unknown | 50 | 39% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 17 | 13% |
| Biochemistry, Genetics and Molecular Biology | 13 | 10% |
| Nursing and Health Professions | 11 | 9% |
| Pharmacology, Toxicology and Pharmaceutical Science | 6 | 5% |
| Agricultural and Biological Sciences | 5 | 4% |
| Other | 19 | 15% |
| Unknown | 57 | 45% |
Attention Score in Context
This research output has an Altmetric Attention Score of 20. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 April 2018.
All research outputs
#1,696,351
of 24,217,893 outputs
Outputs from Inflammopharmacology
#44
of 615 outputs
Outputs of similar age
#36,952
of 427,421 outputs
Outputs of similar age from Inflammopharmacology
#4
of 11 outputs
Altmetric has tracked 24,217,893 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 615 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.0. This one has done particularly well, scoring higher than 93% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 427,421 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 91% of its contemporaries.
We're also able to compare this research output to 11 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.