| Title |
Traditional Food Items in Ogimi, Okinawa: l-Serine Content and the Potential for Neuroprotection
|
|---|---|
| Published in |
Current Nutrition Reports, February 2017
|
| DOI | 10.1007/s13668-017-0191-0 |
| Pubmed ID | |
| Authors |
Paul Alan Cox, James S. Metcalf |
| Abstract |
Ogimi village is renowned for its aging population. We sought to determine if the l-serine content of their diet could account for their neurological health. The most frequently consumed food items, including tofu and seaweeds, are rich in the dietary amino acid l-serine. l-serine content of the Ogimi diet >8 grams/day for Ogimi women significantly exceeds the average American dietary intake of 2.5 grams/day for women >70 years old. Our hypothesis that the high l-serine content of the Ogimi diet is related to the paucity of tangle diseases among villagers is buttressed by in vivo results with non-human primates where dietary l-serine slowed development of neurofibrillary tangles and β-amyloid plaques by up to 85% and a human clinical trial finding that l-serine at 15 grams/day twice daily slows functional decline in ALS patients. Analysis of the Ogimi diet suggests that l-serine should be evaluated for therapeutic potential as a neuroprotective agent. |
X Demographics
The data shown below were collected from the profiles of 32 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 7 | 22% |
| United States | 5 | 16% |
| United Kingdom | 1 | 3% |
| Venezuela, Bolivarian Republic of | 1 | 3% |
| Unknown | 18 | 56% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 25 | 78% |
| Practitioners (doctors, other healthcare professionals) | 4 | 13% |
| Scientists | 2 | 6% |
| Science communicators (journalists, bloggers, editors) | 1 | 3% |
Mendeley readers
The data shown below were compiled from readership statistics for 68 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 68 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 13 | 19% |
| Researcher | 11 | 16% |
| Student > Bachelor | 10 | 15% |
| Student > Doctoral Student | 3 | 4% |
| Student > Ph. D. Student | 3 | 4% |
| Other | 7 | 10% |
| Unknown | 21 | 31% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 12 | 18% |
| Biochemistry, Genetics and Molecular Biology | 6 | 9% |
| Immunology and Microbiology | 3 | 4% |
| Medicine and Dentistry | 3 | 4% |
| Social Sciences | 3 | 4% |
| Other | 16 | 24% |
| Unknown | 25 | 37% |
Attention Score in Context
This research output has an Altmetric Attention Score of 32. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 February 2022.
All research outputs
#1,165,077
of 24,417,958 outputs
Outputs from Current Nutrition Reports
#56
of 365 outputs
Outputs of similar age
#25,940
of 428,268 outputs
Outputs of similar age from Current Nutrition Reports
#1
of 2 outputs
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