| Title |
Fecal Microbiota Transplantation: Indications, Methods, Evidence, and Future Directions
|
|---|---|
| Published in |
Current Gastroenterology Reports, July 2013
|
| DOI | 10.1007/s11894-013-0337-1 |
| Pubmed ID | |
| Authors |
Thomas J. Borody, Sudarshan Paramsothy, Gaurav Agrawal |
| Abstract |
Fecal microbiota transplantation (FMT) has attracted great interest in recent years, largely due to the global Clostridium difficile infection (CDI) epidemic and major advances in metagenomic sequencing of the gastrointestinal (GI) microbiota, with growing understanding of its structure and function. FMT is now recommended as the most effective therapy for relapsing CDI and, with further refinement, may even be used in "first-time" CDI. There is interest also in other conditions related to GI dysbiosis--for example, inflammatory bowel disease, irritable bowel syndrome, obesity, and diabetes mellitus--although quality evidence is at present lacking. A few trials are now underway in FMT for ulcerative colitis. Many unanswered questions remain, including FMT methodology--for example, optimal route of administration, what makes a "good donor," safety issues, and long-term effects of FMT. |
X Demographics
The data shown below were collected from the profiles of 11 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 18% |
| Canada | 1 | 9% |
| United States | 1 | 9% |
| Unknown | 7 | 64% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 7 | 64% |
| Practitioners (doctors, other healthcare professionals) | 4 | 36% |
Mendeley readers
The data shown below were compiled from readership statistics for 436 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Portugal | 1 | <1% |
| Germany | 1 | <1% |
| Chile | 1 | <1% |
| France | 1 | <1% |
| Panama | 1 | <1% |
| Israel | 1 | <1% |
| United Kingdom | 1 | <1% |
| Japan | 1 | <1% |
| United States | 1 | <1% |
| Other | 0 | 0% |
| Unknown | 427 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 79 | 18% |
| Student > Ph. D. Student | 67 | 15% |
| Student > Master | 58 | 13% |
| Researcher | 51 | 12% |
| Student > Doctoral Student | 28 | 6% |
| Other | 86 | 20% |
| Unknown | 67 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 127 | 29% |
| Agricultural and Biological Sciences | 75 | 17% |
| Biochemistry, Genetics and Molecular Biology | 46 | 11% |
| Immunology and Microbiology | 30 | 7% |
| Pharmacology, Toxicology and Pharmaceutical Science | 16 | 4% |
| Other | 56 | 13% |
| Unknown | 86 | 20% |
Attention Score in Context
This research output has an Altmetric Attention Score of 46. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 February 2023.
All research outputs
#914,752
of 25,654,806 outputs
Outputs from Current Gastroenterology Reports
#20
of 600 outputs
Outputs of similar age
#7,297
of 207,407 outputs
Outputs of similar age from Current Gastroenterology Reports
#1
of 11 outputs
Altmetric has tracked 25,654,806 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 600 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.3. This one has done particularly well, scoring higher than 96% of its peers.
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We're also able to compare this research output to 11 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 90% of its contemporaries.