| Title |
Body mass index, abdominal fatness, fat mass and the risk of atrial fibrillation: a systematic review and dose–response meta-analysis of prospective studies
|
|---|---|
| Published in |
European Journal of Epidemiology, February 2017
|
| DOI | 10.1007/s10654-017-0232-4 |
| Pubmed ID | |
| Authors |
Dagfinn Aune, Abhijit Sen, Sabrina Schlesinger, Teresa Norat, Imre Janszky, Pål Romundstad, Serena Tonstad, Elio Riboli, Lars J. Vatten |
| Abstract |
Different adiposity measures have been associated with increased risk of atrial fibrillation, however, results have previously only been summarized for BMI. We therefore conducted a systematic review and meta-analysis of prospective studies to clarify the association between different adiposity measures and risk of atrial fibrillation. PubMed and Embase databases were searched up to October 24th 2016. Summary relative risks (RRs) were calculated using random effects models. Twenty-nine unique prospective studies (32 publications) were included. Twenty-five studies (83,006 cases, 2,405,381 participants) were included in the analysis of BMI and atrial fibrillation. The summary RR was 1.28 (95% confidence interval: 1.20-1.38, I(2) = 97%) per 5 unit increment in BMI, 1.18 (95% CI: 1.12-1.25, I(2) = 73%, n = 5) and 1.32 (95% CI: 1.16-1.51, I(2) = 91%, n = 3) per 10 cm increase in waist and hip circumference, respectively, 1.09 (95% CI: 1.02-1.16, I(2) = 44%, n = 4) per 0.1 unit increase in waist-to-hip ratio, 1.09 (95% CI: 1.02-1.16, I(2) = 94%, n = 4) per 5 kg increase in fat mass, 1.10 (95% CI: 0.92-1.33, I(2) = 90%, n = 3) per 10% increase in fat percentage, 1.10 (95% CI: 1.08-1.13, I(2) = 74%, n = 10) per 5 kg increase in weight, and 1.08 (95% CI: 0.97-1.19, I(2) = 86%, n = 2) per 5% increase in weight gain. The association between BMI and atrial fibrillation was nonlinear, p nonlinearity < 0.0001, with a stronger association at higher BMI levels, however, increased risk was observed even at a BMI of 22-24 compared to 20. In conclusion, general and abdominal adiposity and higher body fat mass increase the risk of atrial fibrillation. |
X Demographics
The data shown below were collected from the profiles of 24 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 8 | 33% |
| United States | 5 | 21% |
| Colombia | 1 | 4% |
| Italy | 1 | 4% |
| Mexico | 1 | 4% |
| Unknown | 8 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 18 | 75% |
| Practitioners (doctors, other healthcare professionals) | 5 | 21% |
| Scientists | 1 | 4% |
Mendeley readers
The data shown below were compiled from readership statistics for 98 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 98 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 13 | 13% |
| Student > Ph. D. Student | 12 | 12% |
| Student > Master | 10 | 10% |
| Researcher | 9 | 9% |
| Professor > Associate Professor | 5 | 5% |
| Other | 12 | 12% |
| Unknown | 37 | 38% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 36 | 37% |
| Nursing and Health Professions | 8 | 8% |
| Biochemistry, Genetics and Molecular Biology | 5 | 5% |
| Economics, Econometrics and Finance | 2 | 2% |
| Sports and Recreations | 2 | 2% |
| Other | 9 | 9% |
| Unknown | 36 | 37% |
Attention Score in Context
This research output has an Altmetric Attention Score of 15. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 May 2017.
All research outputs
#2,386,510
of 25,450,869 outputs
Outputs from European Journal of Epidemiology
#344
of 1,806 outputs
Outputs of similar age
#49,322
of 432,354 outputs
Outputs of similar age from European Journal of Epidemiology
#9
of 22 outputs
Altmetric has tracked 25,450,869 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,806 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 39.0. This one has done well, scoring higher than 80% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 432,354 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 22 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 63% of its contemporaries.