Title |
Nrf2 protects against pulmonary fibrosis by regulating the lung oxidant level and Th1/Th2 balance
|
---|---|
Published in |
Respiratory Research, March 2010
|
DOI | 10.1186/1465-9921-11-31 |
Pubmed ID | |
Authors |
Norihiro Kikuchi, Yukio Ishii, Yuko Morishima, Yuichi Yageta, Norihiro Haraguchi, Ken Itoh, Masayuki Yamamoto, Nobuyuki Hizawa |
Abstract |
Pulmonary fibrosis is a progressive and lethal disorder. Although the precise mechanisms of pulmonary fibrosis are not fully understood, oxidant/antioxidant and Th1/Th2 balances may play an important role in many of the processes of inflammation and fibrosis. The transcription factor Nrf2 acts as a critical regulator for various inflammatory and immune responses by controlling oxidative stress. We therefore investigated the protective role of Nrf2 against the development of pulmonary fibrosis. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 73 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
India | 1 | 1% |
Russia | 1 | 1% |
Unknown | 71 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 19 | 26% |
Researcher | 14 | 19% |
Student > Master | 7 | 10% |
Student > Doctoral Student | 6 | 8% |
Professor > Associate Professor | 6 | 8% |
Other | 10 | 14% |
Unknown | 11 | 15% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 18 | 25% |
Medicine and Dentistry | 12 | 16% |
Biochemistry, Genetics and Molecular Biology | 9 | 12% |
Pharmacology, Toxicology and Pharmaceutical Science | 8 | 11% |
Immunology and Microbiology | 4 | 5% |
Other | 9 | 12% |
Unknown | 13 | 18% |
Attention Score in Context
This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 December 2023.
All research outputs
#5,240,751
of 25,374,917 outputs
Outputs from Respiratory Research
#655
of 3,062 outputs
Outputs of similar age
#23,169
of 110,169 outputs
Outputs of similar age from Respiratory Research
#2
of 10 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done well and is in the 79th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,062 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.9. This one has done well, scoring higher than 78% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 110,169 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 78% of its contemporaries.
We're also able to compare this research output to 10 others from the same source and published within six weeks on either side of this one. This one has scored higher than 8 of them.