Title |
Recent advances in genetic modification systems for Actinobacteria
|
---|---|
Published in |
Applied Microbiology and Biotechnology, February 2017
|
DOI | 10.1007/s00253-017-8156-1 |
Pubmed ID | |
Authors |
Yu Deng, Xi Zhang, Xiaojuan Zhang |
Abstract |
Actinobacteria are extremely important to human health, agriculture, and forests. Because of the vast differences of the characteristics of Actinobacteria, a lot of genetic tools have been developed for efficiently manipulating the genetics. Although there are a lot of successful examples of engineering Actinobacteria, they are still more difficult to be genetically manipulated than other model microorganisms such as Saccharomyces cerevisiae, Escherichia coli, and Bacillus subtilis etc. due to the diverse genomics and biochemical machinery. Here, we review the methods to introduce heterologous DNA into Actinobacteria and the available genetic modification tools. The trends and problems existing in engineering Actinobacteria are also covered. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 74 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 11 | 15% |
Student > Bachelor | 11 | 15% |
Student > Master | 10 | 14% |
Researcher | 8 | 11% |
Professor | 4 | 5% |
Other | 14 | 19% |
Unknown | 16 | 22% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 21 | 28% |
Agricultural and Biological Sciences | 16 | 22% |
Immunology and Microbiology | 6 | 8% |
Pharmacology, Toxicology and Pharmaceutical Science | 3 | 4% |
Chemistry | 3 | 4% |
Other | 7 | 9% |
Unknown | 18 | 24% |