| Title |
Emotion-specific nocebo effects: an fMRI study
|
|---|---|
| Published in |
Brain Imaging and Behavior, February 2017
|
| DOI | 10.1007/s11682-017-9675-1 |
| Pubmed ID | |
| Authors |
Anne Schienle, Carina Höfler, Sonja Übel, Albert Wabnegger |
| Abstract |
The neurobiological mechanisms of nocebos are still poorly understood. Thirty-eight women participated in a 'smell study' using functional magnetic resonance imaging. They were presented with an odorless stimulus (distilled water) together with the verbal suggestion that this fluid has an aversive odor which enhances disgust feelings. The nocebo was presented while the participants viewed disgusting, fear-inducing, and neutral images. Participants' affective and neuronal responses during nocebo administration were compared with those in a control condition without nocebo. Twenty-nine women (76%) reported perceiving a slightly unpleasant and arousing odor. These 'nocebo responders' experienced increased disgust during the presentation of disgusting images in combination with the nocebo and showed enhanced left orbitofrontal cortex (OFC) activation. It has been suggested that the OFC is involved in the generation of placebo/nocebo-related expectations and appraisals. This region showed increased functional connectivity with areas involved in interoception (insula), autobiographical memories (hippocampus), and odor imagery (piriform cortex) during nocebo administration. The nocebo-induced change in brain activation was restricted to the disgust condition. Implications for psychotherapy are discussed. |
X Demographics
The data shown below were collected from the profiles of 9 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Switzerland | 1 | 11% |
| Norway | 1 | 11% |
| Japan | 1 | 11% |
| United States | 1 | 11% |
| Venezuela, Bolivarian Republic of | 1 | 11% |
| Unknown | 4 | 44% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 8 | 89% |
| Scientists | 1 | 11% |
Mendeley readers
The data shown below were compiled from readership statistics for 72 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 72 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 12 | 17% |
| Student > Ph. D. Student | 9 | 13% |
| Student > Doctoral Student | 7 | 10% |
| Student > Bachelor | 7 | 10% |
| Researcher | 6 | 8% |
| Other | 13 | 18% |
| Unknown | 18 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Psychology | 20 | 28% |
| Neuroscience | 11 | 15% |
| Medicine and Dentistry | 9 | 13% |
| Nursing and Health Professions | 3 | 4% |
| Agricultural and Biological Sciences | 2 | 3% |
| Other | 5 | 7% |
| Unknown | 22 | 31% |
Attention Score in Context
This research output has an Altmetric Attention Score of 16. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 September 2023.
All research outputs
#2,251,447
of 25,373,627 outputs
Outputs from Brain Imaging and Behavior
#98
of 1,182 outputs
Outputs of similar age
#41,500
of 319,419 outputs
Outputs of similar age from Brain Imaging and Behavior
#4
of 35 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,182 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.6. This one has done particularly well, scoring higher than 91% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 319,419 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 87% of its contemporaries.
We're also able to compare this research output to 35 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 91% of its contemporaries.