| Title |
Endocrine Disruptors and Obesity
|
|---|---|
| Published in |
Current Obesity Reports, February 2017
|
| DOI | 10.1007/s13679-017-0240-4 |
| Pubmed ID | |
| Authors |
Philippa D. Darbre |
| Abstract |
The purpose of this review was to summarise current evidence that some environmental chemicals may be able to interfere in the endocrine regulation of energy metabolism and adipose tissue structure. Recent findings demonstrate that such endocrine-disrupting chemicals, termed "obesogens", can promote adipogenesis and cause weight gain. This includes compounds to which the human population is exposed in daily life through their use in pesticides/herbicides, industrial and household products, plastics, detergents, flame retardants and as ingredients in personal care products. Animal models and epidemiological studies have shown that an especially sensitive time for exposure is in utero or the neonatal period. In summarising the actions of obesogens, it is noteworthy that as their structures are mainly lipophilic, their ability to increase fat deposition has the added consequence of increasing the capacity for their own retention. This has the potential for a vicious spiral not only of increasing obesity but also increasing the retention of other lipophilic pollutant chemicals with an even broader range of adverse actions. This might offer an explanation as to why obesity is an underlying risk factor for so many diseases including cancer. |
X Demographics
The data shown below were collected from the profiles of 35 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 11 | 31% |
| United Kingdom | 2 | 6% |
| Ireland | 2 | 6% |
| Spain | 2 | 6% |
| Ecuador | 1 | 3% |
| Ghana | 1 | 3% |
| Australia | 1 | 3% |
| Venezuela, Bolivarian Republic of | 1 | 3% |
| Turkey | 1 | 3% |
| Other | 3 | 9% |
| Unknown | 10 | 29% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 26 | 74% |
| Practitioners (doctors, other healthcare professionals) | 5 | 14% |
| Scientists | 2 | 6% |
| Science communicators (journalists, bloggers, editors) | 2 | 6% |
Mendeley readers
The data shown below were compiled from readership statistics for 542 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 542 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 72 | 13% |
| Student > Bachelor | 71 | 13% |
| Student > Master | 67 | 12% |
| Researcher | 42 | 8% |
| Student > Doctoral Student | 25 | 5% |
| Other | 77 | 14% |
| Unknown | 188 | 35% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 75 | 14% |
| Biochemistry, Genetics and Molecular Biology | 56 | 10% |
| Nursing and Health Professions | 41 | 8% |
| Agricultural and Biological Sciences | 34 | 6% |
| Pharmacology, Toxicology and Pharmaceutical Science | 31 | 6% |
| Other | 92 | 17% |
| Unknown | 213 | 39% |
Attention Score in Context
This research output has an Altmetric Attention Score of 142. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 March 2024.
All research outputs
#296,535
of 25,756,911 outputs
Outputs from Current Obesity Reports
#24
of 427 outputs
Outputs of similar age
#6,866
of 451,293 outputs
Outputs of similar age from Current Obesity Reports
#2
of 13 outputs
Altmetric has tracked 25,756,911 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 427 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 40.3. This one has done particularly well, scoring higher than 94% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 451,293 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 84% of its contemporaries.