| Title |
Nasal Oxytocin for Social Deficits in Childhood Autism: A Randomized Controlled Trial
|
|---|---|
| Published in |
Journal of Autism and Developmental Disorders, July 2013
|
| DOI | 10.1007/s10803-013-1899-3 |
| Pubmed ID | |
| Authors |
Mark R. Dadds, Elayne MacDonald, Avril Cauchi, Katrina Williams, Florence Levy, John Brennan |
| Abstract |
The last two decades have witnessed a surge in research investigating the application of oxytocin as a method of enhancing social behaviour in humans. Preliminary evidence suggests oxytocin may have potential as an intervention for autism. We evaluated a 5-day 'live-in' intervention using a double-blind randomized control trial. 38 male youths (7-16 years old) with autism spectrum disorders were administered 24 or 12 international units (depending on weight) intranasal placebo or oxytocin once daily over four consecutive days. The oxytocin or placebo was administered during parent-child interaction training sessions. Parent and child behaviours were assessed using parent reports, clinician ratings, and independent observations, at multiple time points to measure side-effects; social interaction skills; repetitive behaviours; emotion recognition and diagnostic status. Compared to placebo, intranasal oxytocin did not significantly improve emotion recognition, social interaction skills, or general behavioral adjustment in male youths with autism spectrum disorders. The results show that the benefits of nasal oxytocin for young individuals with autism spectrum disorders may be more circumscribed than suggested by previous studies, and suggest caution in recommending it as an intervention that is broadly effective. |
X Demographics
The data shown below were collected from the profiles of 19 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 11% |
| Germany | 2 | 11% |
| United Kingdom | 2 | 11% |
| Australia | 1 | 5% |
| France | 1 | 5% |
| Canada | 1 | 5% |
| Unknown | 10 | 53% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 13 | 68% |
| Scientists | 6 | 32% |
Mendeley readers
The data shown below were compiled from readership statistics for 456 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | <1% |
| Germany | 2 | <1% |
| Netherlands | 1 | <1% |
| United Kingdom | 1 | <1% |
| Brazil | 1 | <1% |
| Spain | 1 | <1% |
| China | 1 | <1% |
| Unknown | 446 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 83 | 18% |
| Student > Master | 68 | 15% |
| Student > Bachelor | 50 | 11% |
| Researcher | 44 | 10% |
| Student > Doctoral Student | 28 | 6% |
| Other | 82 | 18% |
| Unknown | 101 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Psychology | 130 | 29% |
| Medicine and Dentistry | 56 | 12% |
| Neuroscience | 44 | 10% |
| Agricultural and Biological Sciences | 23 | 5% |
| Social Sciences | 21 | 5% |
| Other | 62 | 14% |
| Unknown | 120 | 26% |
Attention Score in Context
This research output has an Altmetric Attention Score of 74. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 November 2021.
All research outputs
#587,004
of 25,654,806 outputs
Outputs from Journal of Autism and Developmental Disorders
#168
of 5,484 outputs
Outputs of similar age
#4,404
of 210,455 outputs
Outputs of similar age from Journal of Autism and Developmental Disorders
#2
of 59 outputs
Altmetric has tracked 25,654,806 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 5,484 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.4. This one has done particularly well, scoring higher than 96% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 210,455 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 59 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 96% of its contemporaries.